Vadim Frolov

Ikerbasque Research Professor, UPV/EHU and Biophysics Institute (CSIC-UPV/EHU)

Group leader at the Biophysics Institute (CSIC-UPV/EHU).

Research line:

Biophysics of cellular and model membranes; membrane dynamics, fusion and fission; mechanics and thermodynamics of small membrane systems.

Researcher, group leader; A.N. Frumkin Institute of Electrochemistry, Moscow, Russia; Senior Research Fellow, National Institutes of Health, Bethesda, USA.

PhD in biophysics, 1998, the Moscow State University.

2023

Article / Molecular Sensing and Manipulation of Protein Oligomerization in Membrane Nanotubes with Bolaamphiphilic Foldamers

Journal of the American Chemical Society

Aftahy, K.; Arrasate, P.; Bashkirov, P.V.; Kuzmin, P.I.; Maurizot, V.; Huc, I.; Frolov, V.A.

2022

Review / Molecular Shape Solution for Mesoscopic Remodeling of Cellular Membranes

Annual Review of Biophysics

Bashkirov, P.V.; Kuzmin, P.I.; Vera Lillo, J.; Frolov, V.A.

2021

Article / Nonlinear material and ionic transport through membrane nanotubes

Biochimica et Biophysica Acta - Biomembranes

Ivchenkov, D.V.; Kuzmin, P.I.; Galimzyanov, T.R.; Shnyrova, A.V.; Bashkirov, P.V.; Frolov, V.A.

2020

Article / Electro-physiological methods to detection of membrane leakage and hemifission by Dynamin1

Methods in Molecular Biology

Bashkirov P.V., Chekashkina K.V., Shnyrova V.A., Frolov V.A.

Article / Reconstitution and real-time quantification of membrane remodeling by single proteins and protein complexes

Nature Protocols

Bashkirov PV, Kuzmin PI, Chekashkina K, Arrasate P, Vera Lillo J, Shnyrova VA, Frolov VA

Article / Reconstitution and real-time quantification of membrane remodeling by single proteins and protein complexes

Nature Protocols

Bashkirov, P.V.; Kuzmin, P.I.; Chekashkina, K.; Arrasate, P.; Vera Lillo, J.; Shnyrova, A.V.; Frolov, V.A.

2019

Article / Dynamic constriction and fission of endoplasmic reticulum membranes by reticulon

Nature Communications

Espadas, J.; Pendin, D.; Bocanegra, R.; Escalada, A.; Misticoni, G.; Trevisan, T.; Velasco del Olmo, A.; Montagna, A.; Bova, S.; Ibarra, B.; Kuzmin, P.I.; Bashkirov, P.V.; Shnyrova, A.V.; Frolov, V.A.; Daga, A.

2018

Review / The 2018 biomembrane curvature and remodeling roadmap

Journal of Physics D: Applied Physics

Bassereau, P.; Jin, R.; Baumgart, T.; Deserno, M.; Dimova, R.; Frolov, V.A.; Bashkirov, P.V.; Grubmüller, H.; Jahn, R.; Risselada, H.J.; Johannes, L.; Kozlov, M.M.; Lipowsky, R.; Pucadyil, T.J.; Zeno, W.F.; Stachowiak, J.C.; Stamou, D.; Breuer, A.; Lauritsen, L.; Simon, C.; Sykes, C.; Voth, G.A.; Weikl, T.R.

2016

Article / Synthesis, lipid membrane incorporation, and ion permeability testing of carbon nanotube porins

Nature Protocols

Tunuguntla, R.H.; Escalada, A.; A Frolov, V.; Noy, A.

Review / Membrane fission by dynamin: what we know and what we need to know

EMBO Journal

Antonny, B.; Burd, C.; De Camilli, P.; Chen, E.; Daumke, O.; Faelber, K.; Ford, M.; Frolov, V.A.; Frost, A.; Hinshaw, J.E.; Kirchhausen, T.; Kozlov, M.M.; Lenz, M.; Low, H.H.; McMahon, H.; Merrifield, C.; Pollard, T.D.; Robinson, P.J.; Roux, A.; Schmid, S.

2015

Article / A hemi-fission intermediate links two mechanistically distinct stages of membrane fission

Nature

Mattila, J.P.; Shnyrova, A.V.; Sundborger, A.C.; Hortelano, E.R.; Fuhrmans, M.; Neumann, S.; Müller, M.; Hinshaw, J.E.; Schmid, S.L.; Frolov, V.A.

Article / Geometry of membrane fission

Chemistry and Physics of Lipids

Frolov, V.A.; Escalada, A.; Akimov, S.A.; Shnyrova, A.V.

2014

Article / Stochastic transport through carbon nanotubes in lipid bilayers and live cell membranes

Nature

Geng, J.; Kim, K.; Zhang, J.; Escalada, A.; Tunuguntla, R.; Comolli, L.R.; Allen, F.I.; Shnyrova, A.V.; Cho, K.R.; Munoz, D.; Wang, Y.M.; Grigoropoulos, C.P.; Ajo-Franklin, C.M.; Frolov, V.A.; Noy, A.

2013

Article / Geometric catalysis of membrane fission driven by flexible dynamin rings

Science

Shnyrova, A.V.; Bashkirov, P.V.; Akimov, S.A.; Pucadyil, T.J.; Zimmerberg, J.; Schmid, S.L.; Frolov, V.A.

2011

Article / Dynamin: Functional design of a membrane fission catalyst

Annual Review of Cell and Developmental Biology

Schmid, S.L.; Frolov, V.A.

Article / Variation of lipid membrane composition caused by strong bending

Biologicheskie Membrany

Bashkirov, P.V.; Chekashkina, K.V.; Akimov, S.A.; Kuzmin, P.I.; Frolov, V.A.

Article / Variation of lipid membrane composition caused by strong bending

Biochemistry (Moscow) Supplement Series A: Membrane and Cell Biology

Bashkirov, P.V.; Chekashkina, K.V.; Akimov, S.A.; Kuzmin, P.I.; Frolov, V.A.

Article / Reconstitution of proapoptotic BAK function in liposomes reveals a dual role for mitochondrial lipids in the BAK-driven membrane permeabilization process

Journal of Biological Chemistry

Landeta, O.; Landajuela, A.; Gil, D.; Taneva, S.; DiPrimo, C.; Sot, B.; Valle, M.; Frolov, V.A.; Basañez, G.

Article / Lipid polymorphisms and membrane shape

Cold Spring Harbor Perspectives in Biology

Frolov, V.A.; Shnyrova, A.V.; Zimmerberg, J.

2010

Review / Cooperative elastic stresses, the hydrophobic effect, and lipid tilt in membrane remodeling

FEBS Letters

Frolov, V.A.; Zimmerberg, J.

Cuantificación de deformaciones nanoscópicas en la membrana del nanotubo mediante medidas de conductancia eléctrica.