Igor Tascón

Ikerbasque Research Fellow, Biofisika Institute

Ikerbasque research fellow at the Structural biology of disease mechanism lab in the Instituto Biofisika (UPV/EHU-CSIC).

Research line:

Structural biology of membrane proteins.

Previous research experience at Goethe Frankfurt University (Germany), Helsinki University (Finland) and CICbioGUNE (Bizkaia).

PhD in Molecular Biology and Biomedicine (2013) from University of the Basque Country.

Publicaciones

2024

Article / Purification of functional recombinant human mitochondrial Hsp60

Methods in Enzymology

Weiss, C.; Berruezo, A.G.; Seraidy, S.; Parnas, A.; Tascón, I.; Ubarretxena-Belandia, I.; Azem, A.

Article / Structural basis for regulation of a CBASS-CRISPR-Cas defense island by a transmembrane anti-σ factor and its ECF σ partner

Science Advances

Bernal-Bernal, D.; Pantoja-Uceda, D.; López-Alonso, J.P.; López-Rojo, A.; López-Ruiz, J.A.; Galbis-Martínez, M.; Ochoa-Lizarralde, B.; Tascón, I.; Elías-Arnanz, M.; Ubarretxena-Belandia, I.; Padmanabhan, S.

Article / A resurrected ancestor of Cas12a expands target access and substrate recognition for nucleic acid editing and detection

Nature Biotechnology

Jabalera, Y.; Tascón, I.; Samperio, S.; López-Alonso, J.P.; Gonzalez-Lopez, M.; Aransay, A.M.; Abascal-Palacios, G.; Beisel, C.L.; Ubarretxena-Belandia, I.; Perez-Jimenez, R.

2023

Article / Cyclic di-AMP traps proton-coupled K<sup>+</sup> transporters of the KUP family in an inward-occluded conformation

Nature Communications

Fuss, M.F.; Wieferig, J.P.; Corey, R.A.; Hellmich, Y.; Tascón, I.; Sousa, J.S.; Stansfeld, P.J.; Vonck, J.; Hänelt, I.

Article / Structural and functional insights into the delivery of a bacterial Rhs pore-forming toxin to the membrane

Nature Communications

González-Magaña, A.; Tascón, I.; Altuna-Alvarez, J.; Queralt-Martín, M.; Colautti, J.; Velázquez, C.; Zabala, M.; Rojas-Palomino, J.; Cárdenas, M.; Alcaraz, A.; Whitney, J.C.; Ubarretxena-Belandia, I.; Albesa-Jové, D.

2021

Article / Conformational plasticity underlies membrane fusion induced by an HIV sequence juxtaposed to the lipid envelope

Scientific Reports

de la Arada, I.; Torralba, J.; Tascón, I.; Colom, A.; Ubarretxena-Belandia, I.; Arrondo, J.L.R.; Apellániz, B.; Nieva, J.L.

2020

Article / Structural insight into the membrane targeting domain of the Legionella deAMPylase SidD

PLoS Pathogens

Tascón, I.; Li, X.; Lucas, M.; D'Anna, N.; Vidaurrazaga, A.; Lin, Y.H.; Rojas, A.L.; Hierro, A.; Machner, M.P.