Edurne Rujas

Ikerbasque Research Fellow, UPV/EHU

Currently works in the Department of Pharmacy and Food Sciences in the Faculty of Pharmacy (UPV/EHU) in the PharmaNanoGene research group (Lascaray Research Center)

Research line:

Antibody engineering for therapeutic purposes and the development of lipid nanoparticle platforms for their in vivo delivery

Extraordinary Award on Graduation, Fellowship to carry out specialized studies abroad from the Government of the Basque Country (Master), predoctoral fellowship from the Government of the Basque Country, Extraordinary Doctorate Award, Marie Skłodowska Curie Global Fellowship (post-doctoral), Connell Award for Best All-Round Postdoctoral Fellow

Previous research experience at the University of Stockholm (Sweden), the University of Tokyo (Japan), the University of Massachusetts Medical School (USA), the Basque Country (Spain) and the Hospital for Sick Children (Canada)

PhD in Biochemistry (2016) from the University of the Basque Country (UPV/EHU) (Spain)

Publications

2024

Article / On the antimicrobial properties and endurance of eugenol and 2-phenylphenol functionalized sol-gel coatings

Heliyon

Suárez-Vega, A.; Berriozabal, G.; Perez de Iriarte, J.; Lorenzo, J.; Álvarez, N.; Dominguez-Meister, S.; Insausti, S.; Rujas, E.; Nieva, J.L.; Brizuela, M.; Braceras, I.

Article / Generation of a Nonbilayer Lipid Nanoenvironment after Epitope Binding Potentiates Neutralizing HIV-1 MPER Antibody

ACS Applied Materials and Interfaces

Insausti, S.; Ramos-Caballero, A.; Wiley, B.; González-Resines, S.; Torralba, J.; Elizaga-Lara, A.; Shamblin, C.; Ojida, A.; Caaveiro, J.M.M.; Zwick, M.B.; Rujas, E.; Domene, C.; Nieva, J.L.

2023

Article / A multi-specific, multi-affinity antibody platform neutralizes sarbecoviruses and confers protection against SARS-CoV-2 in vivo

Science Translational Medicine

Aschner, C.B.; Muthuraman, K.; Kucharska, I.; Cui, H.; Prieto, K.; Nair, M.S.; Wang, M.; Huang, Y.; Christie-Holmes, N.; Poon, B.; Lam, J.; Sultana, A.; Kozak, R.; Mubareka, S.; Rubinstein, J.L.; Rujas, E.; Treanor, B.; Ho, D.D.; Jetha, A.; Julien, J.P.

Article / Modular adjuvant-free pan-HLA-DR-immunotargeting subunit vaccine against SARS-CoV-2 elicits broad sarbecovirus-neutralizing antibody responses

Cell Reports

Kassardjian, A.; Sun, E.; Sookhoo, J.; Muthuraman, K.; Boligan, K.F.; Kucharska, I.; Rujas, E.; Jetha, A.; Branch, D.R.; Babiuk, S.; Barber, B.; Julien, J.P.

2022

Article / Molecular recognition of a membrane-anchored HIV-1 pan-neutralizing epitope

Communications Biology

Torralba, J.; de la Arada, I.; Partida-Hanon, A.; Rujas, E.; Arribas, M.; Insausti, S.; Valotteau, C.; Valle, J.; Andreu, D.; Caaveiro, J.M.M.; Jiménez, M.A.; Apellániz, B.; Redondo-Morata, L.; Nieva, J.L.

Article / Functional Delineation of a Protein–Membrane Interaction Hotspot Site on the HIV-1 Neutralizing Antibody 10E8

International Journal of Molecular Sciences

Insausti, S.; Garcia-Porras, M.; Torralba, J.; Morillo, I.; Ramos-Caballero, A.; de la Arada, I.; Apellaniz, B.; Caaveiro, J.M.M.; Carravilla, P.; Eggeling, C.; Rujas, E.; Nieva, J.L.

Article / Dual Inhibition of Vacuolar-ATPase and TMPRSS2 Is Required for Complete Blockade of SARS-CoV-2 Entry into Cells

Antimicrobial Agents and Chemotherapy

Icho, S.; Rujas, E.; Muthuraman, K.; Tam, J.; Liang, H.; Landreth, S.; Liao, M.; Falzarano, D.; Julien, J.P.; Melnyk, R.A.