Ander Matheu

Ikerbasque Research Professor, Biogipuzkoa Health Research Institute

Neuro-oncology group leader at the Biogipuzkoa Health Research Institute.

Research line:

Characterization of brain cancers and determination of cancer stem cells function.

Over 10 years research experience in cancer. PhD and postodoctoral researcher in the CNIO (Madrid), later moved for 5 years to NIMR (London) and joined Biogipuzkoa in 2011 as neuro-oncology group leader.

Doctor in Molecular Biology from the Autónoma University, Madrid, Spain (2005).

2024

Article / Physical Interventions Restore Physical Frailty and the Expression of CXCL-10 and IL-1β Inflammatory Biomarkers in Old Individuals and Mice

Biomolecules

Marcos-Pérez, D.; Cruces-Salguero, S.; García-Domínguez, E.; Araúzo-Bravo, M.J.; Gómez-Cabrera, M.C.; Viña, J.; Vergara, I.; Matheu, A.

Article / Development of Continuous Assessment of Muscle Quality and Frailty in Older Patients Using Multiparametric Combinations of Ultrasound and Blood Biomarkers: Protocol for the ECOFRAIL Study

JMIR Research Protocols

Virto, N.; Río, X.; Angulo-Garay, G.; Molina, R.G.; Céspedes, A.A.; Zamora, E.B.C.; Jiménez, E.G.; Córcoles, R.A.; Mañas, L.R.; Costa-Grille, A.; Matheu, A.; Marcos-Pérez, D.; Lazcano, U.; Vergara, I.; Arjona, L.; Saeteros, M.; Lopez-De-Ipiña, D.; Coca, A.; Soler, P.A.; Sanabria, S.J.

Article / Centenarian hippocampus displays high levels of astrocytic metallothioneins

Aging Cell

Saenz-Antoñanzas, A.; Muñoz-Culla, M.; Rigo, P.; Ruiz-Barreiro, L.; Moreno-Valladares, M.; Alberro, A.; Cruces-Salguero, S.; Arroyo-Izaga, M.; Arranz, A.M.; Otaegui, D.; Guillemot, F.; Matheu, A.

Article / Identification of a novel gene signature related to prognosis and metastasis in gastric cancer

Cellular Oncology

Elizazu, J.; Artetxe-Zurutuza, A.; Otaegi-Ugartemendia, M.; Moncho-Amor, V.; Moreno-Valladares, M.; Matheu, A.; Carrasco-Garcia, E.

Article / Contilisant+Tubastatin A Hybrids: Polyfunctionalized Indole Derivatives as New HDAC Inhibitor-Based Multitarget Small Molecules with In Vitro and In Vivo Activity in Neurodegenerative Diseases

Journal of Medicinal Chemistry

Toledano-Pinedo, M.; Porro-Pérez, A.; Schäker-Hübner, L.; Romero, F.; Dong, M.; Samadi, A.; Almendros, P.; Iriepa, I.; Bautista-Aguilera, O.M.; Rodríguez-Fernández, M.M.; Solana-Manrique, C.; Sanchis, I.; Mora-Morell, A.; Rodrìguez, A.C.; Sànchez-Pérez, A.M.; Knez, D.; Gobec, S.; Bellver-Sanchis, A.; Pérez, B.; Dobrydnev, A.V.; Artetxe-Zurutuza, A.; Matheu, A.; Siwek, A.; Wolak, M.; Satała, G.; Bojarski, A.J.; Doroz-Płonka, A.; Handzlik, J.; Godyń, J.; Więckowska, A.; Paricio, N.; Griñán-Ferré, C.; Hansen, F.K.; Marco-Contelles, J.

Letter / Analysis of response of centenarians of the Basque Country to COVID-19

Journal of the American Geriatrics Society

Cruces-Salguero, S.; Larrañaga, I.; García-Galindo, A.; Armañanzas, R.; Mar, J.; Matheu, A.

2023

Article / Blood RNA-Seq profiling reveals a set of circular RNAs differentially expressed in frail individuals

Immunity and Ageing

Iparraguirre, L.; Alberro, A.; Iñiguez, S.G.; Muñoz-Culla, M.; Vergara, I.; Matheu, A.; Otaegui, D.

Article / Metabolic rewiring induced by ranolazine improves melanoma responses to targeted therapy and immunotherapy

Nature Metabolism

Redondo-Muñoz, M.; Rodriguez-Baena, F.J.; Aldaz, P.; Caballé-Mestres, A.; Moncho-Amor, V.; Otaegi-Ugartemendia, M.; Carrasco-Garcia, E.; Olias-Arjona, A.; Lasheras-Otero, I.; Santamaria, E.; Bocanegra, A.; Chocarro, L.; Grier, A.; Dzieciatkowska M, M.; Bigas, C.; Martin, J.; Urdiroz-Urricelqui, U.; Marzo, F.; Santamaria, E.; Kochan, G.; Escors, D.; Larrayoz, I.M.; Heyn, H.; D’Alessandro, A.; Attolini, C.S.O.; Matheu, A.; Wellbrock, C.; Benitah, S.A.; Sanchez-Laorden, B.; Arozarena, I.

Article / KRT5+/p63+ Stem Cells Undergo Senescence in the Human Lung with Pathological Aging

Aging and Disease

Moreno-Valladares, M.; Moncho-Amor, V.; Silva, T.M.; Garcés, J.P.; Álvarez-Satta, M.; Matheu, A.

Article / Descriptive and predictive analysis identify centenarians' characteristics from the Basque population

Frontiers in Public Health

Cruces-Salguero, S.; Larrañaga, I.; Mar, J.; Matheu, A.

Article / Empowering frail older adults: multicomponent elastic-band exercises and BCAA supplementation unleash physical health and preserve haematological biomarkers

Frontiers in Sports and Active Living

Caldo-Silva, A.; Furtado, G.E.; Chupel, M.U.; Letieri, R.V.; Neves, R.S.; Direto, F.; Barros, M.P.; Bachi, A.L.L.; Matheu, A.; Martins, F.; Massart, A.; Teixeira, A.M.

Article / Current advances in temozolomide encapsulation for the enhancement of glioblastoma treatment

Theranostics

Iturrioz-Rodríguez, N.; Sampron, N.; Matheu, A.

2022

Article / Descriptive and predictive analysis identify centenarian´s characteristics from the Basque population

Frontiers in Public Health, Sec. Aging and Public Health

Sara Cruces-Salguero, Igor Larrañaga, Javier Mar and Ander Matheu*

Article / High levels of HDAC expression correlate with microglial aging.

Expert Opinion Therapeutic Targets.

Auzmendi-Iriarte J, Moreno-Cugnon L, Saenz-Antoñanzas A, Grassi D, de Pancorbo MM, Arevalo MA, Wood IC, Matheu A.

Article / KRT5+/p63+ Stem Cells Undergo Senescence in the Human Lung with Pathological Aging

Aging and Disease

Manuel Moreno-Valladares, Veronica Moncho-Amor, Tulio M Silva, Juan P Garcés, María Álvarez-Satta, Ander Matheu

Article / Development of continuous assessment of frailty and muscle quality in older subjects using multi-parametric omics based on combined ultrasound and blood biomarkers: a study protocol for a cluster randomised controlled trial (ECOFRAIL study)

BMJ Open

Virto N, Rio X, Angulo G, Garcia R, Avendaño-Cespedes A, Cortés E B, Gómez E, Abizanda P, Rodríguez-Mañas L, Matheu A, Lazcano U, Vergara I, Arjona L, Saeteros M, Coca A, Sanabria SJ

Article / High SOX9 Maintains Glioma Stem Cell Activity through a Regulatory Loop Involving STAT3 and PML

International Journal of Molecular Sciences

Aldaz, P. ;Martín-Martín, N. ;Saenz-Antoñanzas, A. ;Carrasco-Garcia, E. ;Álvarez-Satta, M. ;Elúa-Pinin, A. ;Pollard, S.M. ;Lawrie, C.H. ;Moreno-Valladares, M. ;Samprón, N. ;Hench, J. ;Lovell-Badge, R. ;Carracedo, A. ;Matheu, A.

Article / High SOX9 Maintains Glioma Stem Cell Activity through a Regulatory Loop Involving STAT3 and PML

International Journal of Molecular Sciences

Aldaz, P.; Martín‐martín, N.; Saenz‐antoñanzas, A.; Carrasco‐garcia, E.; Álvarez‐satta, M.; Elúa‐pinin, A.; Pollard, S.M.; Lawrie, C.H.; Moreno‐valladares, M.; Samprón, N.; Hench, J.; Lovell‐badge, R.; Carracedo, A.; Matheu, A.

Article / SOX9 Triggers Different Epithelial to Mesenchymal Transition States to Promote Pancreatic Cancer Progression

Cancers

Carrasco-Garcia, E.; Lopez, L.; Moncho-Amor, V.; Carazo, F.; Aldaz, P.; Collado, M.; Bell, D.; Gaafar, A.; Karamitopoulou, E.; Tzankov, A.; Hidalgo, M.; Rubio, Á.; Serrano, M.; Lawrie, C.H.; Lovell-Badge, R.; Matheu, A.

Article / Senescence plays a role in myotonic dystrophy type 1

JCI Insight

García-Puga, M.; Saenz-Antoñanzas, A.; Gerenu, G.; Arrieta-Legorburu, A.; Fernández-Torrón, R.; Zulaica, M.; Saenz, A.; Elizazu, J.; Nogales-Gadea, G.; Gadalla, S.M.; Araúzo-Bravo, M.J.; de Munain, A.L.; Matheu, A.

Article / Norovirus Intestinal Infection and Lewy Body Disease in an Older Patient with Acute Cognitive Impairment

International Journal of Molecular Sciences

Moreno-Valladares, M.; Moncho-Amor, V.; Bernal-Simon, I.; Agirre-Iturrioz, E.; Álvarez-Satta, M.; Matheu, A.

Article / Chaperone-Mediated Autophagy Controls Proteomic and Transcriptomic Pathways to Maintain Glioma Stem Cell Activity

Cancer Research

Auzmendi-Iriarte, J.; Otaegi-Ugartemendia, M.; Carrasco-Garcia, E.; Azkargorta, M.; Diaz, A.; Saenz-Antoñanzas, A.; Andermatten, J.A.; Garcia-Puga, M.; Garcia, I.; Elua-Pinin, A.; Ruiz, I.; Sampron, N.; Elortza, F.; Cuervo, A.M.; Matheu, A.

Article / High levels of HDAC expression correlate with microglial aging

Expert Opinion on Therapeutic Targets

Auzmendi-Iriarte, J.; Moreno-Cugnon, L.; Saenz-Antoñanzas, A.; Grassi, D.; de Pancorbo, M.M.; Arevalo, M.A.; Wood, I.C.; Matheu, A.

Article / Intrinsic role of chaperone-mediated autophagy in cancer stem cell maintenance

Autophagy

Auzmendi-Iriarte, J.; Matheu, A.

Review / Impact of Cancer Stem Cells on Therapy Resistance in Gastric Cancer

Cancers

Otaegi-Ugartemendia, M.; Matheu, A.; Carrasco-Garcia, E.

Review / Targeting Myotonic Dystrophy Type 1 with Metformin

International Journal of Molecular Sciences

García-Puga, M.; Saenz-Antoñanzas, A.; Matheu, A.; de Munain, A.L.

2021

Article / Inflammaging markers characteristic of advanced age show similar levels with frailty and dependency

Scientific Reports

Alberro, A.; Iribarren-Lopez, A.; Sáenz-Cuesta, M.; Matheu, A.; Vergara, I.; Otaegui, D.

Article / The pseudokinase TRIB3 negatively regulates the HER2 receptor pathway and is a biomarker of good prognosis in luminal breast cancer

Cancers

Orea-Soufi, A.; Castillo-Lluva, S.; Salvador-Tormo, N.; Martín-Cabrera, P.; Recuero, S.; Gabicagogeascoa, E.; Moreno-Valladares, M.; Mendiburu-Eliçabe, M.; Blanco-Gómez, A.; Ramos-Pittol, J.M.; García-Taboada, E.; Ocaña, A.; Cimas, F.J.; Matheu, A.; Álvarez-López, I.; Velasco, G.; Lorente, M.

Article / Centenarians as models of healthy aging: Example of REST

Ageing Research Reviews

Marcos-Pérez, D.; Saenz-Antoñanzas, A.; Matheu, A.

Article / Tumor-derived pericytes driven by egfr mutations govern the vascular and immune microenvironment of gliomas

Cancer Research

Segura-Collar, B.; Garranzo-Asensio, M.; Herranz, B.; Hernández-SanMiguel, E.; Cejalvo, T.; Casas, B.S.; Matheu, A.; Pérez-Núñez, Á.; Sepúlveda-Sánchez, J.M.; Hernández-Laín, A.; Palma, V.; Gargini, R.; Sánchez-Gómez, P.

Article / CRISPR/Cas9 deletion of SOX2 regulatory region 2 (SRR2) decreases SOX2 malignant activity in glioblastoma

Cancers

Saenz-Antoñanzas, A.; Moncho-Amor, V.; Auzmendi-Iriarte, J.; Elua-Pinin, A.; Rizzoti, K.; Lovell-Badge, R.; Matheu, A.

Article / In vitro P38MAPK inhibition in aged astrocytes decreases reactive astrocytes, inflammation and increases nutritive capacity after oxygen-glucose deprivation

Aging

Revuelta, M.; Elicegui, A.; Scheuer, T.; Endesfelder, S.; Bührer, C.; Moreno-Cugnon, L.; Matheu, A.; Schmitz, T.

Article / SOX2 is required independently in both stem and differentiated cells for pituitary tumorigenesis in p27-null mice

Proceedings of the National Academy of Sciences of the United States of America

Moncho-Amor, V.; Chakravarty, P.; Galichet, C.; Matheu, A.; Lovell-Badge, R.; Rizzoti, K.

Article / Impact of Chaperone-Mediated Autophagy in Brain Aging: Neurodegenerative Diseases and Glioblastoma

Frontiers in Aging Neuroscience

Auzmendi-Iriarte, J.; Matheu, A.

Article / Identification of a dexamethasone mediated radioprotection mechanism reveals new therapeutic vulnerabilities in glioblastoma

Cancers

Aldaz, P.; Auzmendi‐iriarte, J.; Durántez, M.; Lasheras‐otero, I.; Carrasco‐garcia, E.; Victoria Zelaya, M.; Bragado, L.; Olías‐arjona, A.; Egaña, L.; Samprón, N.; Morilla, I.; Redondo‐muñoz, M.; Rico, M.; Squatrito, M.; Maria‐alonso, M.; Fernández‐irigoyen, J.; Santamaria, E.; Larráyoz, I.M.; Wellbrock, C.; Matheu, A.; Arozarena, I.

2020

Article / Characterization of a new small-molecule inhibitor of HDAC6 in glioblastoma

Cell Death and Disease

Auzmendi-Iriarte, J.; Saenz-Antoñanzas, A.; Mikelez-Alonso, I.; Carrasco-Garcia, E.; Tellaetxe-Abete, M.; Lawrie, C.H.; Sampron, N.; Cortajarena, A.L.; Matheu, A.

Article / Methylation of MGMT promoter does not predict response to temozolomide in patients with glioblastoma in Donostia Hospital

Scientific Reports

Egaña, L.; Auzmendi-Iriarte, J.; Andermatten, J.; Villanua, J.; Ruiz, I.; Elua-Pinin, A.; Aldaz, P.; Querejeta, A.; Sarasqueta, C.; Zubia, F.; Matheu, A.; Samprón, N.

Article / SOX9 promotes tumor progression through the axis BMI1-p21CIP

Scientific Reports

Aldaz, P.; Otaegi-Ugartemendia, M.; Saenz-Antoñanzas, A.; Garcia-Puga, M.; Moreno-Valladares, M.; Flores, J.M.; Gerovska, D.; Arauzo-Bravo, M.J.; Samprón, N.; Matheu, A.; Carrasco-Garcia, E.

Article / CD8+T cells are present at low levels in the white matter with physiological and pathological aging

Aging

Moreno-Valladares, M.; Saenz-Antoĩanzas, A.; Leire, M.C.; Álvarez-Satta, M.; Matheu, A.; Silva, T.M.; Garces, J.P.

Article / CD8+ T cells are increased in the subventricular zone with physiological and pathological aging

Aging Cell

Moreno-Valladares, M.; Moreno-Cugnon, L.; Silva, T.M.; Garcés, J.P.; Saenz-Antoñanzas, A.; Álvarez-Satta, M.; Matheu, A.

Article / Elevated p38mapk activity promotes neural stem cell aging

Aging

Moreno-Cugnon, L.; Arrizabalaga, O.; Llarena, I.; Matheu, A.

Article / Myotonic Dystrophy type 1 cells display impaired metabolism and mitochondrial dysfunction that are reversed by metformin

Aging

García-Puga, M.; Saenz-Antoñanzas, A.; Fernández-Torrón, R.; de Munain, A.L.; Matheu, A.

Article / Erbb4 is required for cerebellar development and malignant phenotype of medulloblastoma

Cancers

Aldaregia, J.; Errarte, P.; Olazagoitia-Garmendia, A.; Gimeno, M.; Javier Uriz, J.; Gershon, T.R.; Garcia, I.; Matheu, A.

Article / Midkine signaling maintains the self-renewal and tumorigenic capacity of glioma initiating cells

Theranostics

López-Valero, I.; Dávila, D.; González-Martínez, J.; Salvador-Tormo, N.; Lorente, M.; Saiz-Ladera, C.; Torres, S.; Gabicagogeascoa, E.; Hernández-Tiedra, S.; García-Taboada, E.; Mendiburu-Eliçabe, M.; Rodríguez-Fornés, F.; Sánchez-Domínguez, R.; Segovia, J.C.; Sánchez-Gómez, P.; Matheu, A.; Sepúlveda, J.M.; Velasco, G.

Review / Relevance of oxidative stress and inflammation in frailty based on human studies and mouse models

Aging

Álvarez-Satta, M.; Berna-Erro, A.; Carrasco-Garcia, E.; Alberro, A.; Saenz-Antoñanzas, A.; Vergara, I.; Otaegui, D.; Matheu, A.

2019

Article / EXPRESSION OF CELLULAR SENESCENCE AND NEURAL STEM CELL MARKERS IN A CASE OF ADVANCED RETINAL FIBROSIS

Aging Medicine

Manuel Moreno-Valladares and Ander Matheu

Article / Description of frail older people profiles according to four screening tools applied in primary care settings: A cross sectional analysis

BMC Geriatrics

Vergara, I.; Mateo-Abad, M.; Saucedo-Figueredo, M.C.; Machón, M.; Montiel-Luque, A.; Vrotsou, K.; Nava Del Val, M.A.; Díez-Ruiz, A.; Güell, C.; Matheu, A.; Bueno, A.; Núñez, J.; Rivas-Ruiz, F.

Article / Expression of cellular senescence and neural stem cell markers in a case of advanced retinal fibrosis

Aging Medicine

Moreno-Valladares, M.; Matheu, A.

Article / Neuronal p38α mediates age-associated neural stem cell exhaustion and cognitive decline

Aging Cell

Moreno-Cugnon, L.; Revuelta, M.; Arrizabalaga, O.; Colie, S.; Moreno-Valladares, M.; Jimenez-Blasco, D.; Gil-Bea, F.; Llarena, I.; Bolaños, J.P.; Nebreda, A.R.; Matheu, A.

Article / SIX1 represses senescence and promotes SOX2-mediated cellular plasticity during tumorigenesis

Scientific Reports

De Lope, C.; Martín-Alonso, S.; Auzmendi-Iriarte, J.; Escudero, C.; Mulet, I.; Larrasa-Alonso, J.; López-Antona, I.; Matheu, A.; Palmero, I.

Article / SOX3 can promote the malignant behavior of glioblastoma cells

Cellular Oncology

Marjanovic Vicentic, J.; Drakulic, D.; Garcia, I.; Vukovic, V.; Aldaz, P.; Puskas, N.; Nikolic, I.; Tasic, G.; Raicevic, S.; Garros-Regulez, L.; Sampron, N.; Atkinson, M.J.; Anastasov, N.; Matheu, A.; Stevanovic, M.

Article / Therapeutic relevance of SOX9 stem cell factor in gastric cancer

Expert Opinion on Therapeutic Targets

Carrasco-Garcia, E.; Álvarez-Satta, M.; García-Puga, M.; Ribeiro, M.L.; Arevalo, S.; Arauzo-Bravo, M.; Matheu, A.

Article / T cells and immune functions of plasma extracellular vesicles are differentially modulated from adults to centenarians

Aging

Alberro, A.; Osorio-Querejeta, I.; Sepúlveda, L.; Fernández-Eulate, G.; Mateo-Abad, M.; Muñoz-Culla, M.; Carregal-Romero, S.; Matheu, A.; Vergara, I.; de Munain, A.L.; Sáenz-Cuesta, M.; Otaegui, D.

Article / SOX2 expression diminishes with ageing in several tissues in mice and humans

Mechanisms of Ageing and Development

Carrasco-Garcia, E.; Moreno-Cugnon, L.; Garcia, I.; Borras, C.; Revuelta, M.; Izeta, A.; Lopez-Lluch, G.; de Pancorbo, M.M.; Vergara, I.; Vina, J.; Matheu, A.

Review / Ischemic stroke in neonatal and adult astrocytes

Mechanisms of Ageing and Development

Revuelta, M.; Elicegui, A.; Moreno-Cugnon, L.; Bührer, C.; Matheu, A.; Schmitz, T.

Review / Liquid biopsy in glioblastoma: Opportunities, applications and challenges

Cancers

Saenz-Antoñanzas, A.; Auzmendi-Iriarte, J.; Carrasco-Garcia, E.; Moreno-Cugnon, L.; Ruiz, I.; Villanua, J.; Egaña, L.; Otaegui, D.; Samprón, N.; Matheu, A.

Review / Primary cilium and brain aging: role in neural stem cells, neurodegenerative diseases and glioblastoma

Ageing Research Reviews

Álvarez-Satta, M.; Moreno-Cugnon, L.; Matheu, A.

2018

Book / segunda edición del Tratado de Geriatría

elsevier

Manuel Moreno-Valladares, Leire Moreno-Cugnon y Ander Matheu

Book / Nora doa gizakia

Leire Moreno-Cugnon y Ander Matheu

Article / SOX2 haploinsufficiency promotes impaired vision at advanced age

oncotarget (gerotarget)

Moreno-Cugnon L, Anasagasti A, Ezquerra-Inchausti M, Izeta A, de la Villa P, Ruiz-Ederra J, Matheu A

Article / PR-LncRNA signature regulates glioma cell activity through expression of SOX factors

Scientific Reports

Torres-Bayona, S.; Aldaz, P.; Auzmendi-Iriarte, J.; Saenz-Antoñanzas, A.; Garcia, I.; Arrazola, M.; Gerovska, D.; Undabeitia, J.; Querejeta, A.; Egaña, L.; Villanúa, J.; Ruiz, I.; Sarasqueta, C.; Urculo, E.; Araúzo-Bravo, M.J.; Huarte, M.; Samprón, N.; Matheu, A.

Article / SOX2 haploinsufficiency promotes impaired vision at advanced age

Oncotarget

Moreno-Cugnon, L.; Anasagasti, A.; Ezquerra-Inchausti, M.; Izeta, A.; De La Villa, P.; Ruiz-Ederra, J.; Matheu, A.

Review / Targeting mTOR as a therapeutic approach in medulloblastoma

International Journal of Molecular Sciences

Aldaregia, J.; Odriozola, A.; Matheu, A.; Garcia, I.

Review / Towards precision medicine: linking genetic and cellular heterogeneity in gastric cancer

Therapeutic Advances in Medical Oncology

Carrasco-Garcia, E.; García-Puga, M.; Arevalo, S.; Matheu, A.

Review / Primary cilium and glioblastoma

Therapeutic Advances in Medical Oncology

Álvarez-Satta, M.; Matheu, A.

Review / Integrin α7: A novel promising target in glioblastoma stem cells

Stem Cell Investigation

Carrasco-Garcia, E.; Auzmendi-Iriarte, J.; Matheu, A.

2017

Book / eBook

SM Online Scientific Resources LLC

Garcia I, Carrasco-Garcia E, Garros-Regulez L, Aldaz P, Moreno-Cugnon L, Arrizabalaga O, Undabeitia J, Torres-Bayona S, Villanua J, Ruiz I, Egaña L, Sampron N, and Matheu A

Chapter / Gastric Cancer Book

InTech open sicence

Carrasco-Garcia E, García-Puga M, Moreno M, Sampron N, Arevalo S & Matheu A

Article / Clinical prognostic factors are better outcome predictors than molecular factors in glioblastoma multiforme

Clinics in Oncology

Samprón N, Undabeitia J, Torres-Bayona S, Aldaz P, Carrasco-Garcia E, Arrazola M, Villanua J, Egaña L, Caballero MC, Etxegoien I, Bollar A , Querejeta A, Armendáriz M, Torres P, Pardo E, Liceaga G, Urtasun M, Ruiz I, Matheu A, Urculo E

Article / Stem cell-like transcriptional reprogramming mediates metastatic resistance to mTOR inhibition

Oncogene

Mateo, F.; Arenas, E.J.; Aguilar, H.; Serra-Musach, J.; De Garibay, G.R.; Boni, J.; Maicas, M.; Du, S.; Iorio, F.; Herranz-Ors, C.; Islam, A.; Prado, X.; Llorente, A.; Petit, A.; Vidal, A.; Català, I.; Soler, T.; Venturas, G.; Rojo-Sebastian, A.; Serra, H.; Cuadras, D.; Blanco, I.; Lozano, J.; Canals, F.; Sieuwerts, A.M.; De Weerd, V.; Look, M.P.; Puertas, S.; García, N.; Perkins, A.S.; Bonifaci, N.; Skowron, M.; Gómez-Baldó, L.; Hernández, V.; Martínez-Aranda, A.; Martínez-Iniesta, M.; Serrat, X.; Cerón, J.; Brunet, J.; Barretina, M.P.; Gil, M.; Falo, C.; Fernández, A.; Morilla, I.; Pernas, S.; Plà, M.J.; Andreu, X.; Seguí, M.A.; Ballester, R.; Castellà, E.; Nellist, M.; Morales, S.; Valls, J.; Velasco, A.; Matias-Guiu, X.; Figueras, A.; Sánchez-Mut, J.V.; Sánchez-Céspedes, M.; Cordero, A.; Gómez-Miragaya, J.; Palomero, L.; Gómez, A.; Gajewski, T.F.; Cohen, E.E.W.; Jesiotr, M.; Bodnar, L.; Quintela-Fandino, M.; López-Bigas, N.; Valdés-Mas, R.; Puente, X.S.; Viñals, F.; Casanovas, O.; Graupera, M.; Hernández-Losa, J.; Ramóny Cajal, S.; García-Alonso, L.; Saez-Rodriguez, J.; Esteller, M.; Sierra, A.; Martín-Martín, N.; Matheu, A.; Carracedo, A.; González-Suárez, E.; Nanjundan, M.; Cortés, J.; Lázaro, C.; Odero, M.D.; Martens, J.W.M.; Moreno-Bueno, G.; Barcellos-Hoff, M.H.; Villanueva, A.; Gomis, R.R.; Pujana, M.A.

Article / High expression of MKP1/DUSP1 counteracts glioma stem cell activity and mediates HDAC inhibitor response

Oncogenesis

Arrizabalaga, O.; Moreno-Cugnon, L.; Auzmendi-Iriarte, J.; Aldaz, P.; De Cáceres, I.I.; Garros-Regulez, L.; Moncho-Amor, V.; Torres-Bayona, S.; Perniá, O.; Pintado-Berninches, L.; Carrasco-Ramirez, P.; Cortes-Sempere, M.; Rosas, R.; Sanchez-Gomez, P.; Ruiz, I.; Caren, H.; Pollard, S.; Garcia, I.; Sacido, A.A.; Lovell-Badge, R.; Belda-Iniesta, C.; Sampron, N.; Perona, R.; Matheu, A.

Article / SOX17 regulates cholangiocyte differentiation and acts as a tumor suppressor in cholangiocarcinoma

Journal of Hepatology

Merino-Azpitarte, M.; Lozano, E.; Perugorria, M.J.; Esparza-Baquer, A.; Erice, O.; Santos-Laso, Á.; O'Rourke, C.J.; Andersen, J.B.; Jiménez-Agüero, R.; Lacasta, A.; D'Amato, M.; Briz, Ó.; Jalan-Sakrikar, N.; Huebert, R.C.; Thelen, K.M.; Gradilone, S.A.; Aransay, A.M.; Lavín, J.L.; Fernández-Barrena, M.G.; Matheu, A.; Marzioni, M.; Gores, G.J.; Bujanda, L.; Marin, J.J.G.; Banales, J.M.

Article / Helicobacter pylori infection modulates the expression of miRNAs associated with DNA mismatch repair pathway

Molecular Carcinogenesis

Santos, J.C.; Brianti, M.T.; Almeida, V.R.; Ortega, M.M.; Fischer, W.; Haas, R.; Matheu, A.; Ribeiro, M.L.

Article / Oncogenic activity of SOX1 in glioblastoma

Scientific Reports

Garcia, I.; Aldaregia, J.; Vicentic, J.M.; Aldaz, P.; Moreno-Cugnon, L.; Torres-Bayona, S.; Carrasco-Garcia, E.; Garros-Regulez, L.; Egaña, L.; Rubio, A.; Pollard, S.; Stevanovic, M.; Sampron, N.; Matheu, A.

Editorial / Diffuse intrinsic pontine gliomas: The future of combination therapy with mTORC1/2 inhibitors and radiation

Translational Cancer Research

Garcia, I.; Aldareguia, J.; Matheu, A.

Note / Autophagy in stem cell aging

Aging Cell

Revuelta, M.; Matheu, A.

Review / Increased Arf/p53 activity in stem cells, aging and cancer

Aging Cell

Carrasco-Garcia, E.; Moreno, M.; Moreno-Cugnon, L.; Matheu, A.

2016

Chapter / eBook “Recent Advances in Gastric Cancer

Carrasco-Garcia E, Santos JC, García-Puga M, Sampron N, Ribeiro ML & Matheu A

Article / Cancer risk in myotonic dystrophy type 1 is sex related and linked to downregulation of miRNA200-141 tumor suppressor cluster

Neurology

Fernández Torrón R, Garcia-Puga M, Emparanza JI, Maneiro M, Cobo AM, Poza Aldea JJ, Espinal JB, Zulaica M, Ruiz I, Martorell L, Otaegui D, Matheu A, Lopez de Munain A.

Article / High levels of SOX9 induce gastric cancer progression through a regulatory loop with WNT canonical signaling

Cancer Research

Carvalho JL, Carrasco-Garcia E, Garcia-Puga M, Aldaz P, Montes M, Fernandez-Reyes M, Candida de Oliveira C, Lawrie CH, Arauzo-Bravo M, Ribeiro ML & Matheu A

Article / Stratification and therapeutic potential of PML in metastatic breast cancer

Nature Communications

Martín-Martín, N.; Piva, M.; Urosevic, J.; Aldaz, P.; Sutherland, J.D.; Fernández-Ruiz, S.; Arreal, L.; Torrano, V.; Cortazar, A.R.; Planet, E.; Guiu, M.; Radosevic-Robin, N.; Garcia, S.; Macías, I.; Salvador, F.; Domenici, G.; Rueda, O.M.; Zabala-Letona, A.; Arruabarrena-Aristorena, A.; Zúñiga-García, P.; Caro-Maldonado, A.; Valcárcel-Jiménez, L.; Sánchez-Mosquera, P.; Varela-Rey, M.; Martínez-Chantar, M.L.; Anguita, J.; Ibrahim, Y.H.; Scaltriti, M.; Lawrie, C.H.; Aransay, A.M.; Iovanna, J.L.; Baselga, J.; Caldas, C.; Barrio, R.; Serra, V.; Dm Vivanco, M.; Matheu, A.; Gomis, R.R.; Carracedo, A.

Article / SOX9 elevation acts with canonical WNT signaling to drive gastric cancer progression

Cancer Research

Santos, J.C.; Carrasco-Garcia, E.; Garcia-Puga, M.; Aldaz, P.; Montes, M.; Fernandez-Reyes, M.; De Oliveira, C.C.; Lawrie, C.H.; Arauzo-Bravo, M.J.; Ribeiro, M.L.; Matheu, A.

Article / Identification and Characterization of the Dermal Panniculus Carnosus Muscle Stem Cells

Stem Cell Reports

Naldaiz-Gastesi, N.; Goicoechea, M.; Alonso-Martín, S.; Aiastui, A.; López-Mayorga, M.; García-Belda, P.; Lacalle, J.; San José, C.; Araúzo-Bravo, M.J.; Trouilh, L.; Anton-Leberre, V.; Herrero, D.; Matheu, A.; Bernad, A.; García-Verdugo, J.M.; Carvajal, J.J.; Relaix, F.; Lopez de Munain, A.; García-Parra, P.; Izeta, A.

Article / SOX9-regulated cell plasticity in colorectal metastasis is attenuated by rapamycin

Scientific Reports

Carrasco-Garcia, E.; Lopez, L.; Aldaz, P.; Arevalo, S.; Aldaregia, J.; Eganã, L.; Bujanda, L.; Cheung, M.; Sampron, N.; Garcia, I.; Matheu, A.

Article / Inflammaging and frailty status do not result in an increased extracellular vesicle concentration in circulation

International Journal of Molecular Sciences

Alberro, A.; Sáenz-Cuesta, M.; Muñoz-Culla, M.; Mateo-Abad, M.; Gonzalez, E.; Carrasco-Garcia, E.; Araúzo-Bravo, M.J.; Matheu, A.; Vergara, I.; Otaegui, D.

Article / MTOR inhibition decreases SOX2-SOX9 mediated glioma stem cell activity and temozolomide resistance

Expert Opinion on Therapeutic Targets

Garros-Regulez, L.; Aldaz, P.; Arrizabalaga, O.; Moncho-Amor, V.; Carrasco-Garcia, E.; Manterola, L.; Moreno-Cugnon, L.; Barrena, C.; Villanua, J.; Ruiz, I.; Pollard, S.; Lovell-Badge, R.; Sampron, N.; Garcia, I.; Matheu, A.

Article / Human exceptional longevity: Transcriptome from centenarians is distinct from septuagenarians and reveals a role of Bcl-xL in successful aging

Aging

Borras, C.; Abdelaziz, K.M.; Gambini, J.; Serna, E.; Inglés, M.; de la Fuente, M.; Garcia, I.; Matheu, A.; Sanchís, P.; Belenguer, A.; Errigo, A.; Avellana, J.A.; Barettino, A.; Lloret-Fernández, C.; Flames, N.; Pes, G.; Rodriguez-Mañas, L.; Viña, J.

Review / Paradoxical role of SOX2 in gastric cancer

American Journal of Cancer Research

Carrasco-Garcia, E.; Santos, J.C.; Garcia, I.; Brianti, M.; García-Puga, M.; Pedrazzoli, J.; Matheu, A.; Ribeiro, M.L.

Short Survey / Targeting SOX2 as a therapeutic strategy in glioblastoma

Frontiers in Oncology

Garros-Regulez, L.; Garcia, I.; Carrasco-Garcia, E.; Lantero, A.; Aldaz, P.; Moreno-Cugnon, L.; Arrizabalaga, O.; Undabeitia, J.; Torres-Bayona, S.; Villanua, J.; Ruiz, I.; Egaña, L.; Sampron, N.; Matheu, A.

2014

Chapter / Topics in Anti-Cancer-Research Volume 3

Atta-ur-Rahman and Khurshid Zaman

Estefania Carrasco-Garcia, Nicolas Sampron, Paula Aldaz, Olatz Arrizabalaga, Jorge Villanua, Cristina Barrena, Irune Ruiz, Mariano Arrazola, Charles Lawrie and Ander Matheu

Article / sncRNA signature found in microvesicles of GBM patient serum serves as diagnostic marker

Neurooncology

Manterola L, Guruceaga E, Gallego J, Gonzalez-Huarriz M, Jauregui P, Segura V, Sampron N, Barrena C, Ruiz I, Tejada S, Diez-Valle R, Agirre A, Ayuso-Sacido A, Rodriguez J, Gonzalez A, Matheu A, Tuñon T, Zazpe I, Xipell E, Lopez de Munain A, García-Foncill

Article / Role of SOX Family of Transcription Factors in Glioblastoma.

American Journal of Cancer Research.

Acanda de la Rocha, Sampron N, Alonso MM, Matheu A,

Article / Global analysis of the human p53 transcriptional network unveils a lncRNA tumor suppressor signature.

Nature Communications

Sanchez Y, Segura V, Athie A, Marchese F, González J, Marín-Béjar O, Bujanda L, Guo S, Matheu A and Huarte M.

2013

Article / Therapeutic Strategies Targeting Glioblastoma Stem Cells. Recent Patents on Anti-Cancer Drug Discovery

Recent Patents on Anti-Cancer Drug Discovery

Carrasco-Garcia E, Sampron N, Aldaz P, Arrizabalga O, Villanua J, Barrena C, Ruiz I, Arrazola M, Lawrie CH and Matheu A,

Review / Therapeutic strategies targeting Glioblastoma stem cells

Recent Patents on Anti-Cancer Drug Discovery

Carrasco-Garcia, E.; Sampron, N.; Aldaz, P.; Arrizabalaga, O.; Villanua, J.; Barrena, C.; Ruiz, I.; Arrazola, M.; Lawrie, C.; Matheu, A.

2012

Article / P27kip directly contributes to Sox2 transcriptional repression during stem cell differentiation

Cell Stem Cell

Li H, Collado M, Villasante A, Matheu A, Lynch C, Cañamero M, Rizzoti K, Carneiro C, Martínez G, Vidal A, Lovell-Badge R and Serrano M

Article / Betacellulin promotes cell proliferation in the neural stem cell niche

PNAS

Gomez-Gaviro M, Sesay A, Scott C, Matheu A, Booth S and Lovell-Badge R

Envejecimiento y cáncer en la Distrofia Miotónica tipo 1: Nuevas estrategias terapéuticas

University of the Basque Country

Mikel García-Puga - Finished

Identification of ERBB4 and SOX1 role in central nervous system tumors. Implication in medulloblastoma and glioblastoma

University of the Basque Country

Juncal Aldaregia - Finished

Análisis de los factores predictores de fragilidad y su impacto en la evolución postquirúrgica del paciente con tumor cerebral

University of the Basque Country

Patricia Torres - Finished

Identificación de la función y el mecanismo molecular del factor de transcripción SOX9 como regulador de las células madre tumorales; perspectivas terapéuticas

Universidad del País Vasco

Paula Aldaz - Finished

Impacto clínico de un patrón de cadenas largas de ARN no codificantes en el glioblastoma multiforme

Universidad del País Vasco

Sergio Torres-Bayona - Finished

Modulación de SOX2 mediante la inhibición de mTOR y su implicación en quimiorresistencia y células madre del cáncer en glioblastoma multiforme

Universidad País Vasco

Laura Garrós - Finished

Mecanismos reguladores de las células madre neurales: implicación en los procesos de envejecimiento y cáncer

University Autonoma Madrid

Olatz Arrizabalaga - Finished

Critical role of SOX2 and p38MAPK in stem cell exhaustion, cognitive activity and organismal ageing

University of the Basque Country

Leire Moreno Cugnon - Finished

DETERMINACIÓN DEL VALOR PRONÓSTICO Y PREDICTIVO DE RESPUESTA A TEMOZOLOMIDA DE LA METILACION DEL PROMOTOR DE MGMT EN PACIENTES CON GLIOBLASTOMAS MULTIFORMES TRATADOS EN EL HOSPITAL UNIVERSITARIO DE DONOSTIA.

Universidad del País Vasco

Larraitz Egaña - Finished

2020

Role of p38MAPK in ageing

University of the Basque Country

2019

Big data for analysis of medulloblastoma

Tecnum

2018

Papel de Sox1 en meduloblastoma

Universidad del País Vasco

Identificación de genes implicados en la acción oncogénica del factor de transcripción SOX9 en cáncer gástrico

Universidad del País Vasco

2017

TRF1-aren eragina glioblastoman: glioma zelula ametan duen adierazpena eta inhibizioaren potentzial terapeutikoa

University of the Basque Country

Determinación de la función de SOX1 en la iniciación y la progresión del cáncer gástrico ?

Universidad del País Vasco

Study of ErbB4 in Medulloblastoma

Universidad del País Vasco

2016

Papel de las células madre tumorales en la quimioresistencia del adenocarcinoma de páncreas

Universitat Rovira Virgili

Función de la Autofagia mediada por chaperonas en glioblastoma multiforme

University of the Basque Country

2015

Función de la expresión del factor de transcripción SOX1 en la diferenciación de las células madre de glioblastoma

University of the Basque Country

2014

¿Puede BMI1 ser un gen supresor de tumores en la línea U87?

UPV

Mecanismos moleculares implicados en el envejecimiento de las células madre neurales

University of the Basque Country

2013

ESTUDIO DE LA FUNCIÓN DE SOX9 EN GLIOBLASTOMA

UPV

2023

Universidad País Vasco, Bilbao. Master Neurociencias. Heterogeneidad y plasticidad celular en la malignidad del glioma.

2022

Universidad País Vasco, Bilbao. Master Neurociencias. Heterogeneidad y plasticidad celular en la malignidad del glioma.

2021

Invited Speaker "Chaperone-mediated autophagy maintains glioma stem cell activity controlling different proteomic and transcriptomic pathways." XIII Symposium of GEINO meeting. Dic 2021.

2019

Universidad País Vasco, Bilbao. Master Neurociencias. Heterogeneidad y plasticidad celular en la malignidad del glioma.

2018

Fundación GUNE. 'Prolongar la vida, hasta dónde? ¿a quién? ¿seremos a-mortales? ¿para qué?'

Heterogeneidad y plasticidad celular en la malignidad del glioma. Master Universidad del País Vasco

Director del Curso de Verano "INVESTIGACIÓN E INNOVACIÓN EN LA FRAGILIDAD Y EL ENVEJECIMIENTO " de la Universidad del País Vasco

Presentación "Modelos pre-clínicos para el estudio de la fragilidad" dentro del Curso de Verano de "Investigación e innovación en la fragilidad y el envejecimiento"

2017

Universidade Sao Francisco, Sao Paulo, Brasil. "Se puede atacar el cáncer y el envejecimiento con las mismas herramientas ?"

Programa de Patología Neurosensorial del CIBERER, Madrid. "Abordaje integral de la fragilidad: desde la célula hasta la clínica"

Ponencia en curso verano UPV-EHU “HACIA EL ENVEJECIMIENTO SALUDABLE A TRAVÉS DE LA INNOVACIÓN Y LA INVESTIGACIÓN”. San Sebastian, Spain. Función de las células madre en los procesos cancerosos y en el envejecimiento.

Ponencia en curso verano UPV-EHU “Felicidad y Longevidad: Luces y Sombras de la Agenda Social de las Sociedades desarrolladas”. San Sebastian, Spain. Fragilidad funcional y cognitiva asociada a la pérdida de las células madre adultas.

2016

Curso de Verano Universidad del País Vasco: las claves de la longevidad

2015

Vias moleculares implicadas en el envejecimiento celular en Curso de doctorado Universidad Valencia

Curso Biología para médicos dentro de meeting sociedad española geriatría y gerontología. "Envejecimiento celular"

Curso de Doutorado Universidade Sao Francisco, Brasil "Celulas tronco como terapia frente al cancer".

Universidade Campinas, Sao Paulo, Brasil, Master de Doctorado. Celulas tronco como terapia frente al cancer y envejecimiento.

2014

Curso Verano “Envejecimiento saludable. reto para la investigación e innovación en salud”,

Curso Mestrado “Stem Cells and regenerative Medicine”, Universidade Campinas, Sao Paulo, Brasil

Universidade Sao Francisco, Sao Paulo, Brasil. Stem cells function on ageing.

2013

XV Reunión: “LINEAS DE INVESTIGACIÓN EN NEURONCOLOGÍA” DE LA Sociedad Española Neurocirugía.

2012

Master doctorado “envejecimiento y ejercicio físico”, Universidad Valencia.

Donostia Hospital tumor commission general meeting,

2012

The manuscript Castillo S, Matheu A, Mariani N, Carretero J, Lopez-Rios F, Lovell-Badge R, Sanchez-Cespedes M. (2012) Identification of Novel Transcriptional Targets Links the SRY-HMG box gene SOX4 with the Development of Small Cell Lung Cancer. Cancer Research. 1,176-86. Won the Maria Julia Castillo prize

2023

Conference Paper | Ultrasound quantitative monitoring of muscle quality changes in sarcopenia patients after supervised exercise intervention

IEEE International Ultrasonics Symposium, IUS - Conference Paper

Saeteros, M.; Virto, N.; Oyarzábal, I.; De Frutos, X.R.; García, R.; Avendaño, A.; Cortes, E.B.; Gómez, E.; Abizanda, P.; Rodríguez-Mañas, L.; Matheu, A.; Lazcano, U.; Vergara, I.; Arjona, L.; Coca, A.; Sanabria, S.J.

2018

Poster presentation | SOX2 regulates stem cell ageing, cognitive function and healthspan

Molecular , Cellular and Organismal Hallmarks of Aging - Poster presentation

Ander Matheu, Leire Moreno-Cugnon , Miren Revuelta, Manuel Moreno-Valladares,

Poster presentation | p38MAPkinase activity promotes age-related neural stem cell decline and cognitive impairment

Molecular , Cellular and Organismal Hallmarks of Aging - Poster presentation

Leire Moreno-Cugnon, Miren Revuelta, Manuel Moreno-Valladares, Irantzu Llarena, Angel Nebreda and Ander Matheu

Poster presentation | Cell senescence and stem cells in human pulmonary tissue homeostasis

Molecular , Cellular and Organismal Hallmarks of Aging - Poster presentation

Manuel Moreno-Valladares, Tulio Silva, Iraide Bernal, Leire Moreno-Cugnon, Miren Revuelta, Ander Matheu

Poster presentation | p38MAPkinase activity promotes age-related neurogenesis decline and cognitive impairment

Aging and Metabolism - Poster presentation

p38MAPkinase activity promotes age-related neurogenesis decline and cognitive impairment Leire Moreno-Cugnon, Miren Revuelta, Manuel Moreno-Valladares, and Ander Matheu

Poster presentation | Role of ErbB4 in Medulloblastoma and its modulation as a new therapeutic target

XXXIV Reunión de la Sociedad Española de Neurocirugía Pediátrica - Poster presentation

Aldaregia Juncal, Olazagoitia Ane, Matheu Ander, Garcia Idoia.

Poster presentation | p38MAPkinase activity promotes age-related neurogenesis decline and cognitive impairment

stem cell dynamics through life - Poster presentation

Leire Moreno-Cugnon, Miren Revuelta, Manuel Moreno-Valladares, and Ander Matheu

Poster presentation | El envejecimiento y la fragilidad no resultan en una mayor concentración de vesículas extracelulares en circulación

8 Reunión Annual de la Sociedad Española de Medicina Geriátrica - Poster presentation

Alberro A, Vergara I, Otaegui D, Matheu A.

2017

Invited talk | Generation of mouse models to study frailty: function of stem cells.

Envejecimiento active y Fragilidad. Jornadas Internacionales SEMEG-CIBERFES. - Invited talk

Ander Matheu

Invited talk | Stem Cell exhaustion promotes frailty

10 jornadas de comunicación, Sesión conjunta CIBERES y CIBERFES. - Invited talk

Ander Matheu

Oral presentation | Novel molecular mechanisms of immunoresistance and cancer stem cell activity.

1st ASEICA Educational Symposium in Immunotherapy. - Oral presentation

Saenz A, Aldaz P, Torres-Bayona S, Samprón N and Matheu A.

Oral presentation | Impact of SOX2 haploinsufficiency in longevity and stem cell activity with aging

). IUBMB Focused Meeting on «Molecular aspects of aging and longevity». - Oral presentation

10. Moreno-Cugnon L, Revuelta R, Moreno M, Yndriago L, Ruiz-Ederra J, Izeta A, Matheu A.

Poster presentation | Identification of critical molecular pathways underlying glioblastoma stem cell activity

Primary and secondary brain tumors. CNIO International Meetings. - Poster presentation

Matheu A, Aldaz P, Garcia I, Carrasco-Garcia E, Torres-Bayona S, Villanua J, Ruiz I, Samprón N

Poster presentation | High expression of MKP1 counteracts glioma stem cell activity and mediates HDAC inhibitor response,

1st ASEICA Educational Symposium in Immunotherapy - Poster presentation

Auzmendi-Iriarte J, Moreno-Cugnon L, Arrizabalaga O, Sampron N, Perona R, Matheu A.

Poster presentation | Patient Stratification through critical molecular pathways underlying cellular plasticity and heterogeneity.

Enhancing predictivity in medicines development, EATRIS Meeting. - Poster presentation

11. Matheu A, Aldaz P, Garcia I, Carrasco-Garcia E, Torres-Bayona S, Villanua J, Ruiz I, Samprón N.

2016

Invited talk | A promising path in the molecular labyrinth of central nervous system tumors: Role of SOX family of transcription factors.

Neuroiberia 2016, International Congress of neurosurgery, - Invited talk

Samprón N, Torres-Bayona S, Acanda A, Matheu A, Arrazola M, Undabeitia J, Úrculo E

Oral presentation | Functional role of PML and SOX9 in Glioblastoma Multiforme

Neuroiberia 2016, International Congress of neurosurgery, - Oral presentation

Torres-Bayona S, Aldaz P, Garcia I, Samprón N, Úrculo E, Matheu A

Poster presentation | Functional characterization of the interaction between the stem cell factor SOX2 and the cell cycle regulator p27 in normal and cancerous stem cells.

EACR Meeting - Poster presentation

Veronica Moncho-Amor, Laura Garros, Christophe Galichet, Karine Rizzoti, Ander Matheu, Robin Lovell-Badge

Poster presentation | SOX9 acts with canonical WNT signaling to drive gastric cancer progression

2nd International Conference on Stem Cells and Cancer - Poster presentation

Carrasco-García E. García-Puga M, Santos JC, Ribeiro ML, Matheu A.

Poster presentation | SOX9 and PML regulate glioblastoma stem cell activity

2nd International Conference on Stem Cells and Cancer - Poster presentation

Aldaz P, Garcia I, Torres S, Villanua J, Ruiz I, Samprón N, Matheu A

2015

Conference organization | no

Spanish Society of Gene and celular therapy Congress. - Conference organization

Matheu A

Conference organization | no

57 Spanish Society of Geriatry and Gerontology Congress. - Conference organization

matheu a

Invited talk | Cambios genéticos que regulan la edad cronológica y biológica

57 Spanish Society of Geriatry and Gerontology Congress. - Invited talk

Matheu A,

Oral presentation | SOX9 regulates glioblastoma stem cell activity

II International Symposium on Clinical and Basic Investigation in Glioblastoma, September 2015, - Oral presentation

Matheu A, Aldaz P, Garcia I, Torres S, Villanua J, Ruiz I, Sampron N,

Oral presentation | Novel therapeutic strategies targeting tumor-initiating cells in brain cancers

20th World Congress on Advances in Oncology and 18th International Symposium on Molecular Medicine, - Oral presentation

Matheu A, Garros L, Aldaz P, Arrizabalaga O, Garcia I, Ruiz I, Sampron N, Villanua J,

Poster presentation | SOX9 mediates SOX2 activity in glioblastoma

Trends in Central Nervous System Malignancies, March 2015. - Poster presentation

Matheu A, Garros L, Aldaz P, Garcia I, Ruiz I, Sampron N, Arevalo S, Villanua J,

Poster presentation | Increased Ink4a/Arf locus and p53 gene dosage diminishes age associated neural stem cell and cognitive decline

8th Spanish Society of Gene and celular therapy Congress. Nov 2015. - Poster presentation

Matheu A, Carrasco-Garcia E, Arrizabalaga O,

Poster presentation | Deregulation of SOX9 in tumor initiating cells induces EMT and promotes metastasis and gemcitabine resistance in pancreatic adenocarcinoma

15th ASEICA International Congress. Oct 2015 - Poster presentation

Carrasco-Garcia E, Arevalo S, Aldaz P, Matheu A,

2014

Oral presentation | Increased Ink4a/Arf and p53 gene dosage elongates lifespan and diminished age-associated tissue functional decline

Biology of Human Aging - Oral presentation

Matheu A,

Oral presentation | Increased Ink4a/Arf and p53 gene dosage elongates lifespan and diminished age-associated tissue functional decline

Biology of Human Aging - Oral presentation

Matheu A

Poster presentation | Deregulation of SOX9 in tumor initiating cells

Translational advances in cancer cell signalling and metabolism, - Poster presentation

Matheu A, Carrasco-Garcia E, Aldaz P, Arrizabalaga O, Arevalo S, Sampron N,

2013

Invited talk | Nuevas vías moleculares implicadas en la regulación del envejecimiento.

55 Spanish Society of Geriatry and Gerontology Congress. - Invited talk

Matheu A,

Oral presentation | SOX9 function in Glioblastoma

Encuentro Multidisciplinar en Neurooncología - Oral presentation

Matheu A,

Oral presentation | SOX9 function in Cancer

14th ASEICA International Congress - Oral presentation

Carrasco E, Aldaz P Arrizabalaga O, Garrós L, Matheu A,

Poster presentation | SOX9 function in Cancer

Stem Cells in Translation - Poster presentation

Carrasco E, Aldaz P Arrizabalaga O, Garrós L, Matheu A,

2012

Poster presentation | SOX9 function regulates tissue and cancer stem cells

IDIBELL Cancer Conference on Personalized Cancer Medicine. - Poster presentation

Matheu A, Carrasco E.

Poster presentation | SOX9 function regulates tissue and cancer stem cells

Mechanisms & Models of Cancer. - Poster presentation

Matheu A, Carrasco E.

2005

Invited talk | Investigación Traslacional en Neuro-Oncologia

Praxis 2015 Cancer Meeting - Invited talk

Matheu A, Aldaz P, Sampron N, Arevalo S, Ruiz I, Egaña L,