Abraham Martín

Ikerbasque Research Associate, Achucarro Basque Center for Neuroscience

Group leader of the Laboratory of Neuroimaging and biomarkers of inflammation at Achucarro Basque Center for Neuroscience.

Research line:

Neuroinflammation, Molecular Imaging, Cerebrovascular diseases.

Ramón y Cajal Fellowship (2017).

Previous research experience in Biomedical imaging and Neuroscience in centers in Spain (Institute of Biomedical Research of Barcelona-CSIC and CICbiomaGUNE), France (Institute for Biomedical Imaging-CEA), Greece (Institute of Electronic Structure and Laser-FORTH) and USA (University of California Los Angeles).

Doctor in Neurosciences (2007) from University of Barcelona, Spain.

2024

Article / Multimodal imaging of the role of hyperglycemia following experimental subarachnoid hemorrhage

Journal of Cerebral Blood Flow and Metabolism

Joya, A.; Plaza-García, S.; Padro, D.; Aguado, L.; Iglesias, L.; Garbizu, M.; Gómez-Vallejo, V.; Laredo, C.; Cossío, U.; Torné, R.; Amaro, S.; Planas, A.M.; Llop, J.; Ramos-Cabrer, P.; Justicia, C.; Martín, A.

Article / Urease-powered nanobots for radionuclide bladder cancer therapy

Nature Nanotechnology

Simó, C.; Serra-Casablancas, M.; Hortelao, A.C.; Di Carlo, V.; Guallar-Garrido, S.; Plaza-García, S.; Rabanal, R.M.; Ramos-Cabrer, P.; Yagüe, B.; Aguado, L.; Bardia, L.; Tosi, S.; Gómez-Vallejo, V.; Martín, A.; Patiño, T.; Julián, E.; Colombelli, J.; Llop, J.; Sánchez, S.

Article / Neuroaxonal Injury May Mediate the Association Between Hyperglycemia and Prognosis in Spontaneous Subarachnoid Hemorrhage

Molecular Neurobiology

Santana, D.; Llull, L.; Mosteiro, A.; Pedrosa, L.; Pujol, G.; Zattera, L.; Werner, M.; Martín, A.; Justicia, C.; Chamorro, Á.; Torné, R.; Amaro, S.

Article / Preclinical validation of human recombinant glutamate-oxaloacetate transaminase for the treatment of acute ischemic stroke

iScience

Pérez-Mato, M.; Dopico-López, A.; Akkoc, Y.; López-Amoedo, S.; Correa-Paz, C.; Candamo-Lourido, M.; Iglesias-Rey, R.; López-Arias, E.; Bugallo-Casal, A.; da Silva-Candal, A.; Bravo, S.B.; Chantada-Vázquez, M.d.P.; Arias, S.; Santamaría-Cadavid, M.; Estany-Gestal, A.; Zaghmi, A.; Gauthier, M.A.; Gutiérrez-Fernández, M.; Martin, A.; Llop, J.; Rodríguez, C.; Almeida, Á.; Migliavacca, M.; Polo, E.; Pelaz, B.; Gozuacik, D.; El Yamani, N.; SenGupta, T.; Rundén-Pran, E.; Vivancos, J.; Castellanos, M.; Díez-Tejedor, E.; Sobrino, T.; Rabinkov, A.; Mirelman, D.; Castillo, J.; Campos, F.

Note / Alpha7 nicotinic receptors as potential theranostic targets for experimental stroke

Neural Regeneration Research

Garbizu, M.; Aguado, L.; Martin, A.

Review / Role of Microglia in Stroke

Advances in neurobiology

Cipriani, R.; Domerq, M.; Martín, A.; Matute, C.

2023

Article / Therapeutic effect of α7 nicotinic receptor activation after ischemic stroke in rats

Journal of Cerebral Blood Flow and Metabolism

Aguado, L.; Joya, A.; Garbizu, M.; Plaza-García, S.; Iglesias, L.; Hernández, M.I.; Ardaya, M.; Mocha, N.; Gómez-Vallejo, V.; Cossio, U.; Higuchi, M.; Rodríguez-Antigüedad, A.; Freijo, M.M.; Domercq, M.; Matute, C.; Ramos-Cabrer, P.; Llop, J.; Martín, A.

Article / Assessment of Regional Lung Ventilation with Positron Emission Tomography Using the Radiofluorinated Gas [<sup>18</sup>F]SF6: Application to an Animal Model of Impaired Ventilation

Molecular Imaging and Biology

Passannante, R.; Gómez-Vallejo, V.; Cossío, U.; Ruiz-Cabello, J.; Lekuona, A.; Salinas, V.; Amado-Rodríguez, L.; Albaiceta, G.M.; Martín, A.; Rejc, L.; Llop, J.

Article / Pharmacokinetic Evaluation of New Drugs Using a Multi-Labelling Approach and PET Imaging: Application to a Drug Candidate with Potential Application in Neuromuscular Disorders

Biomedicines

Passannante, R.; Gómez-Vallejo, V.; Sagartzazu-Aizpurua, M.; Vignau Arsuaga, L.; Marco-Moreno, P.; Aldanondo, G.; Vallejo-Illarramendi, A.; Aguiar, P.; Cossío, U.; Martín, A.; Bergare, J.; Kingston, L.; Elmore, C.S.; Morcillo, M.A.; Ferrón, P.; Aizpurua, J.M.; Llop, J.

2022

Article / Longitudinal evaluation of neuroinflammation and oxidative stress in a mouse model of Alzheimer disease using positron emission tomography

Alzheimer's Research and Therapy

Rejc, L.; Gómez-Vallejo, V.; Joya, A.; Arsequell, G.; Egimendia, A.; Castellnou, P.; Ríos-Anglada, X.; Cossío, U.; Baz, Z.; Iglesias, L.; Capetillo-Zarate, E.; Ramos-Cabrer, P.; Martin, A.; Llop, J.

Article / Endovascular administration of magnetized nanocarriers targeting brain delivery after stroke

Journal of Cerebral Blood Flow and Metabolism

Grayston, A.; Zhang, Y.; Garcia-Gabilondo, M.; Arrúe, M.; Martin, A.; Kopcansky, P.; Timko, M.; Kovac, J.; Strbak, O.; Castellote, L.; Belloli, S.; Moresco, R.M.; Picchio, M.; Roig, A.; Rosell, A.

2021

Article / Endovascular administration of magnetized nanocarriers targeting brain delivery after stroke

J Cereb Blood Flow Metab

Grayston A, Zhang Y, Garcia-Gabilondo M, Arrúe M, Martin A, Kopcansky P, Timko M, Kovac J, Strbak O, Castellote L, Belloli S, Moresco RM, Picchio M, Roig A, Rosell A

Article / Fluorine Labeling of Nanoparticles and in Vivo <sup>19</sup>F Magnetic Resonance Imaging

ACS Applied Materials and Interfaces

Arango, J.M.; Padro, D.; Blanco, J.; Lopez-Fernandez, S.; Castellnou, P.; Villa-Valverde, P.; Ruiz-Cabello, J.; Martin, A.; Carril, M.

Article / Longitudinal evaluation of a novel BChE PET tracer as an early in vivo biomarker in the brain of a mouse model for Alzheimer disease

Theranostics

Rejc, L.; Gómez-Vallejo, V.; Joya, A.; Moreno, O.; Egimendia, A.; Castellnou, P.; Ríos-Anglada, X.; Cossío, U.; Baz, Z.; Passannante, R.; Tobalina-Larrea, I.; Ramos-Cabrer, P.; Giralt, A.; Sastre, M.; Capetillo-Zarate, E.; Košak, U.; Knez, D.; Gobec, S.; Marder, M.; Martin, A.; Llop, J.

Article / Opposite alterations of 5HT2A receptor brain density in subjects with schizophrenia: relevance of radiotracers pharmacological profile

Translational Psychiatry

Diez-Alarcia, R.; Muguruza, C.; Rivero, G.; García-Bea, A.; Gómez-Vallejo, V.; Callado, L.F.; Llop, J.; Martín, A.; Meana, J.J.

Review / Evaluation of glial cell proliferation with non-invasive molecular imaging methods after stroke

Neural Regeneration Research

Joya, A.; Martín, A.

2020

Article / In vivo multimodal imaging of adenosine A1 receptors in neuroinflammation after experimental stroke

Theranostics

Joya, A.; Ardaya, M.; Montilla, A.; Garbizu, M.; Plaza-García, S.; Gómez-Vallejo, V.; Padro, D.; Gutiérrez, J.J.; Rios, X.; Ramos-Cabrer, P.; Cossío, U.; Pulagam, K.R.; Higuchi, M.; Domercq, M.; Cavaliere, F.; Matute, C.; Llop, J.; Martín, A.

Article / In vivo PET Imaging of Gliogenesis After Cerebral Ischemia in Rats

Frontiers in Neuroscience

Ardaya, M.; Joya, A.; Padro, D.; Plaza-García, S.; Gómez-Vallejo, V.; Sánchez, M.; Garbizu, M.; Cossío, U.; Matute, C.; Cavaliere, F.; Llop, J.; Martín, A.

2019

Article / Radiochemical examination of transthyretin (TTR) brain penetration assisted by iododiflunisal, a TTR tetramer stabilizer and a new candidate drug for AD

Scientific Reports

Rios, X.; Gómez-Vallejo, V.; Martín, A.; Cossío, U.; Morcillo, M.Á.; Alemi, M.; Cardoso, I.; Quintana, J.; Jiménez-Barbero, J.; Cotrina, E.Y.; Valencia, G.; Arsequell, G.; Llop, J.

2018

Article / Differential effects of FXR or TGR5 activation in cholangiocarcinoma progression

Biochimica et Biophysica Acta - Molecular Basis of Disease

Erice, O.; Labiano, I.; Arbelaiz, A.; Santos-Laso, A.; Munoz-Garrido, P.; Jimenez-Agüero, R.; Olaizola, P.; Caro-Maldonado, A.; Martín-Martín, N.; Carracedo, A.; Lozano, E.; Marin, J.J.; O'Rourke, C.J.; Andersen, J.B.; Llop, J.; Gómez-Vallejo, V.; Padro, D.; Martin, A.; Marzioni, M.; Adorini, L.; Trauner, M.; Bujanda, L.; Perugorria, M.J.; Banales, J.M.

Article / P2X4 receptor controls microglia activation and favors remyelination in autoimmune encephalitis

EMBO Molecular Medicine

Zabala, A.; Vazquez-Villoldo, N.; Rissiek, B.; Gejo, J.; Martin, A.; Palomino, A.; Perez-Samartín, A.; Pulagam, K.R.; Lukowiak, M.; Capetillo-Zarate, E.; Llop, J.; Magnus, T.; Koch-Nolte, F.; Rassendren, F.; Matute, C.; Domercq, M.

Article / In vivo imaging of Α7 nicotinic receptors as a novel method to monitor neuroinflammation after cerebral ischemia

GLIA

Colás, L.; Domercq, M.; Ramos-Cabrer, P.; Palma, A.; Gómez-Vallejo, V.; Padro, D.; Plaza-García, S.; Pulagam, K.R.; Higuchi, M.; Matute, C.; Llop, J.; Martín, A.

Article / PET Imaging of Crossed Cerebellar Diaschisis after Long-Term Cerebral Ischemia in Rats

Contrast Media and Molecular Imaging

Joya, A.; Padro, D.; Gómez-Vallejo, V.; Plaza-García, S.; Llop, J.; Martín, A.

Imaging of lipids as biomarkers of neuroinflammation after stroke