Alexei Verkhratsky

Ikerbasque Research Professor, UPV/EHU

Ikerbasque Research Professor at the Department of Neuroscience, Faculty of Medicine at the University of the Basque Country, UPV/EHU.

Research line:

Neuroscience, Neuroglia, cell signalling, neurodegeneration.

Member of Academia Europaea, Chair of the Physiology & Medicine Section; Member of The German National Academy of Sciences Leopoldina Member of Real Academia Nacional de Farmacia; Member of European Dana Alliance for the Brain.

More than 25 years of experience in research centres in Europe and Asia.

Bogomoletz Institute of Physiology in 1986.

2024

Article / Astrocyte syncytium: From neonatal genesis to aging degeneration

Neural Regeneration Research

Zhou, M.; Zhong, S.; Verkhratsky, A.

Article / Sodium homeostasis and signalling: The core and the hub of astrocyte function

Cell Calcium

Rose, C.R.; Verkhratsky, A.

Article / Alterations of protein homeostasis in Alzheimer’s disease: beyond Procrustean bed of endoplasmic reticulum stress and unfolded protein response

Neural Regeneration Research

Lim, D.; Verkhratsky, A.

Article / Trace metals and astrocytes physiology and pathophysiology

Cell Calcium

Li, B.; Yu, W.; Verkhratsky, A.

Article / Astrocyte chloride, excitatory-inhibitory balance and epilepsy

Neural Regeneration Research

Untiet, V.; Nedergaard, M.; Verkhratsky, A.

Article / APoe from patient-derived astrocytic extracellular vesicles alleviates neuromyelitis optica spectrum disorder in a mouse model

Science Translational Medicine

Jiang, S.; Li, X.; Li, Y.; Chang, Z.; Yuan, M.; Zhang, Y.; Zhu, H.; Xiu, Y.; Cong, H.; Yin, L.; Yu, Z.W.; Fan, J.; He, W.; Shi, K.; Tian, D.C.; Zhang, J.; Verkhratsky, A.; Jin, W.N.; Shi, F.D.

Article / Endothelial DR6 in blood-brain barrier malfunction in Alzheimer’s disease

Cell Death and Disease

Huang, X.; Qi, J.; Su, Y.; Zhou, Y.; Wang, Q.; Huang, T.; Xue, D.; Zeng, Y.; Verkhratsky, A.; Zhou, B.; Chen, H.; Yi, C.

Article / Amyloid precursor protein induces reactive astrogliosis

Acta Physiologica

Velezmoro Jauregui, G.; Vukić, D.; Onyango, I.G.; Arias, C.; Novotný, J.S.; Texlová, K.; Wang, S.; Kovačovicova, K.L.; Polakova, N.; Zelinkova, J.; Čarna, M.; Lacovich, V.; Head, B.P.; Havas, D.; Mistrik, M.; Zorec, R.; Verkhratsky, A.; Keegan, L.; O'Connell, M.A.; Rissman, R.; Stokin, G.B.

Article / Plasma of COVID-19 Patients Does Not Alter Electrical Resistance of Human Endothelial Blood-Brain Barrier In Vitro

Function

Pociūte, A.; Kriaučiūnaite, K.; Kaušyle, A.; Zablockiene, B.; Alčauskas, T.; Jelinskaite, A.; Rudenaite, A.; Jančoriene, L.; Ročka, S.; Verkhratsky, A.; Pivoriūnas, A.

Article / Neuroglia in cognitive reserve

Molecular Psychiatry

Verkhratsky, A.; Zorec, R.

Article / Chronic maternal exposure to low-dose PM2.5 impacts cognitive outcomes in a sex-dependent manner

Environment International

Oliver, B.G.; Huang, X.; Yarak, R.; Bai, X.; Wang, Q.; Zakarya, R.; Reddy, K.D.; Donovan, C.; Kim, R.Y.; Morkaya, J.; Wang, B.; Lung Chan, Y.; Saad, S.; Faiz, A.; Reyk, D.v.; Verkhratsky, A.; Yi, C.; Chen, H.

Editorial / Multiple ions control astroglial excitability, or “Nein, Kalzium, ist NICHT alles”

Acta Physiologica

Verkhratsky, A.; Rose, C.R.

Note / Sleep, calcium and microglia – an (un)expected liaison

Cell Calcium

Garaschuk, O.; Verkhratsky, A.

Review / Bioelectronic Medicine: a multidisciplinary roadmap from biophysics to precision therapies

Frontiers in Integrative Neuroscience

González-González, M.A.; Conde, S.V.; Latorre, R.; Thébault, S.C.; Pratelli, M.; Spitzer, N.C.; Verkhratsky, A.; Tremblay, M.È.; Akcora, C.G.; Hernández-Reynoso, A.G.; Ecker, M.; Coates, J.; Vincent, K.L.; Ma, B.

Review / Targeting connexins: possible game changer in managing neuropathic pain?

Trends in Molecular Medicine

Su, Y.; Verkhratsky, A.; Yi, C.

Review / How astrocytic chloride modulates brain states

BioEssays

Untiet, V.; Verkhratsky, A.

Review / Calcium Signalling in Microglia

Advances in neurobiology

Garaschuk, O.; Verkhratsky, A.

Review / Microglia in Neurodegenerative Diseases

Advances in neurobiology

Awogbindin, I.; Wanklin, M.; Verkhratsky, A.; Tremblay, M.È.

Review / Receptors on Microglia

Advances in neurobiology

Augusto-Oliveira, M.; Tremblay, M.È.; Verkhratsky, A.

Review / General Pathophysiology of Microglia

Advances in neurobiology

Tremblay, M.È.; Verkhratsky, A.

Short Survey / Astrocytes dynamically regulate the blood-brain barrier in the healthy brain

Neural Regeneration Research

Pocit, A.; Pivorinas, A.; Verkhratsky, A.

2023

Article / Neuroanatomical and morphometric study of S100β positive astrocytes in the entorhinal cortex during ageing in the 3xTg-Alzehimer's disease mouse model

Neuroscience Letters

Rodríguez, J.J.; Terzieva, S.; Yeh, C.Y.; Gardenal, E.; Zallo, F.; Verkhratsky, A.; Busquets, X.

Article / Astrocytic chloride is brain state dependent and modulates inhibitory neurotransmission in mice

Nature Communications

Untiet, V.; Beinlich, F.R.M.; Kusk, P.; Kang, N.; Ladrón-de-Guevara, A.; Song, W.; Kjaerby, C.; Andersen, M.; Hauglund, N.; Bojarowska, Z.; Sigurdsson, B.; Deng, S.; Hirase, H.; Petersen, N.C.; Verkhratsky, A.; Nedergaard, M.

Article / The influence of astrocytic leaflet motility on ionic signalling and homeostasis at active synapses

Scientific Reports

Toman, M.; Wade, J.J.; Verkhratsky, A.; Dallas, M.; Bithell, A.; Flanagan, B.; Harkin, J.; McDaid, L.

Article / P2X7R influences tau aggregate burden in human tauopathies and shows distinct signalling in microglia and astrocytes

Brain, Behavior, and Immunity

Beltran-Lobo, P.; Hughes, M.M.; Troakes, C.; Croft, C.L.; Rupawala, H.; Jutzi, D.; Ruepp, M.D.; Jimenez-Sanchez, M.; Perkinton, M.S.; Kassiou, M.; Golde, T.E.; Hanger, D.P.; Verkhratsky, A.; Perez-Nievas, B.G.; Noble, W.

Article / Electroacupuncture prevents astrocyte atrophy to alleviate depression

Cell Death and Disease

Lin, S.S.; Zhou, B.; Chen, B.J.; Jiang, R.T.; Li, B.; Illes, P.; Semyanov, A.; Tang, Y.; Verkhratsky, A.

Article / Astroglia support, regulate and reinforce brain barriers

Neurobiology of Disease

Verkhratsky, A.; Pivoriūnas, A.

Article / Basic Fibroblast Growth Factor Opens and Closes the Endothelial Blood–Brain Barrier in a Concentration-Dependent Manner

Neurochemical Research

Kriaučiūnaitė, K.; Pociūtė, A.; Kaušylė, A.; Verkhratsky, A.; Pivoriūnas, A.

Article / Leptin Attenuates Fear Memory by Inhibiting Astrocytic NLRP3 Inflammasome in Post-traumatic Stress Disorder Model

Neurochemical Research

Ji, M.; Gong, W.; Wang, S.; Zhang, D.; Chen, B.; Li, X.; Wu, X.; Cui, L.; Feng, Y.; Verkhratsky, A.; Li, B.

Article / Astrocyte endfoot formation controls the termination of oligodendrocyte precursor cell perivascular migration during development

Neuron

Su, Y.; Wang, X.; Yang, Y.; Chen, L.; Xia, W.; Hoi, K.K.; Li, H.; Wang, Q.; Yu, G.; Chen, X.; Wang, S.; Wang, Y.; Xiao, L.; Verkhratsky, A.; Fancy, S.P.J.; Yi, C.; Niu, J.

Article / Dissociation Between Neuronal and Astrocytic Calcium Activity in Response to Locomotion in Mice

Function

Fedotova, A.; Brazhe, A.; Doronin, M.; Toptunov, D.; Pryazhnikov, E.; Khiroug, L.; Verkhratsky, A.; Semyanov, A.

Article / A novel murine model of mania

Molecular Psychiatry

Li, X.; Chen, B.; Zhang, D.; Wang, S.; Feng, Y.; Wu, X.; Cui, L.; Ji, M.; Gong, W.; Verkhratsky, A.; Xia, M.; Li, B.

Article / Analysis of the mechanism of Sophorae Flavescentis Radix in the treatment of intractable itching based on network pharmacology and molecular docking

European Review for Medical and Pharmacological Sciences

Xiao, Y.; Wang, R.J.; Zeng, H.K.; Xie, J.; Situ, Y.L.; Kong, S.; Wang, T.T.; Verkhratsky, A.; Nie, H.

Article / Bruton’s tyrosine kinase-bearing B cells and microglia in neuromyelitis optica spectrum disorder

Journal of Neuroinflammation

Liu, Y.; Huang, Z.; Zhang, T.X.; Han, B.; Yang, G.; Jia, D.; Yang, L.; Liu, Q.; Lau, A.Y.L.; Paul, F.; Verkhratsky, A.; Shi, F.D.; Zhang, C.

Article / Mitochondrial malfunction and atrophy of astrocytes in the aged human cerebral cortex

Nature Communications

Popov, A.; Brazhe, N.; Morozova, K.; Yashin, K.; Bychkov, M.; Nosova, O.; Sutyagina, O.; Brazhe, A.; Parshina, E.; Li, L.; Medyanik, I.; Korzhevskii, D.E.; Shenkarev, Z.; Lyukmanova, E.; Verkhratsky, A.; Semyanov, A.

Editorial / Pre-And Postfusion Tuning of Regulated Exocytosis by Cell Metabolites

Function

Zorec, R.; Verkhratsky, A.

Note / Decline of astrocyte Ca2+ signalling in Alzheimer's disease: STIM1 to the rescue!

Cell Calcium

Verkhratsky, A.; Semyanov, A.

Review / Astrocytes in human central nervous system diseases: a frontier for new therapies

Signal Transduction and Targeted Therapy

Verkhratsky, A.; Butt, A.; Li, B.; Illes, P.; Zorec, R.; Semyanov, A.; Tang, Y.; Sofroniew, M.V.

Review / Pathological potential of oligodendrocyte precursor cells: terra incognita

Trends in Neurosciences

Yi, C.; Verkhratsky, A.; Niu, J.

Review / Radial stem astrocytes (aka neural stem cells): Identity, development, physio-pathology, and therapeutic potential

Acta Physiologica

Yeh, C.Y.; Wu, K.Y.; Huang, G.J.; Verkhratsky, A.

Review / The endoplasmic reticulum stress and unfolded protein response in Alzheimer's disease: A calcium dyshomeostasis perspective

Ageing Research Reviews

Lim, D.; Tapella, L.; Dematteis, G.; Genazzani, A.A.; Corazzari, M.; Verkhratsky, A.

Review / Astrocytes in the pathophysiology of neuroinfection

Essays in Biochemistry

Zorec, R.; Verkhratsky, A.

Review / Astrocyte adaptation in Alzheimer's disease: a focus on astrocytic P2X7R

Essays in Biochemistry

Beltran-Lobo, P.; Reid, M.J.; Jimenez-Sanchez, M.; Verkhratsky, A.; Perez-Nievas, B.G.; Noble, W.

2022

Article / Activation of Wnt/β-catenin pathway mitigates blood-brain barrier dysfunction in Alzheimer's disease

Brain

Wang, Q.; Huang, X.; Su, Y.; Yin, G.; Wang, S.; Yu, B.; Li, H.; Qi, J.; Chen, H.; Zeng, W.; Zhang, K.; Verkhratsky, A.; Niu, J.; Yi, C.

Article / Pathological oligodendrocyte precursor cells revealed in human schizophrenic brains and trigger schizophrenia-like behaviors and synaptic defects in genetic animal model

Molecular Psychiatry

Yu, G.; Su, Y.; Guo, C.; Yi, C.; Yu, B.; Chen, H.; Cui, Y.; Wang, X.; Wang, Y.; Chen, X.; Wang, S.; Wang, Q.; Chen, X.; Hu, X.; Mei, F.; Verkhratsky, A.; Xiao, L.; Niu, J.

Article / The neuroprotective mechanism of lithium after ischaemic stroke

Communications Biology

Chen, B.; Zhang, M.; Ji, M.; Zhang, D.; Chen, B.; Gong, W.; Li, X.; Zhou, Y.; Dong, C.; Wen, G.; Zhan, X.; Wu, X.; Yuan, H.; Xu, E.; Xia, M.; Verkhratsky, A.; Li, B.

Article / A high-fat diet changes astrocytic metabolism to promote synaptic plasticity and behavior

Acta Physiologica

Popov, A.; Brazhe, N.; Fedotova, A.; Tiaglik, A.; Bychkov, M.; Morozova, K.; Brazhe, A.; Aronov, D.; Lyukmanova, E.; Lazareva, N.; Li, L.; Ponimaskin, E.; Verkhratsky, A.; Semyanov, A.

Article / Ageing related thyroid deficiency increases brain-targeted transport of liver-derived ApoE4-laden exosomes leading to cognitive impairment

Cell Death and Disease

Zhang, M.; Gong, W.; Zhang, D.; Ji, M.; Chen, B.; Chen, B.; Li, X.; Zhou, Y.; Dong, C.; Wen, G.; Zhan, X.; Wu, X.; Cui, L.; Feng, Y.; Wang, S.; Yuan, H.; Xu, E.; Xia, M.; Verkhratsky, A.; Li, B.

Article / Plasticity of microglia

Biological Reviews

Augusto-Oliveira, M.; Arrifano, G.P.; Delage, C.I.; Tremblay, M.È.; Crespo-Lopez, M.E.; Verkhratsky, A.

Article / Vesicle cholesterol controls exocytotic fusion pore

Cell Calcium

Rituper, B.; Guček, A.; Lisjak, M.; Gorska, U.; Šakanović, A.; Bobnar, S.T.; Lasič, E.; Božić, M.; Abbineni, P.S.; Jorgačevski, J.; Kreft, M.; Verkhratsky, A.; Platt, F.M.; Anderluh, G.; Stenovec, M.; Božič, B.; Coorssen, J.R.; Zorec, R.

Editorial / Editorial: Role of Neuroinflammation in the Neuropsychiatric and Neurological Aspects of COVID-19

Frontiers in Cellular Neuroscience

Tremblay, M.E.; Madore, C.; Tian, L.; Verkhratsky, A.

Note / The great astroglial metabolic revolution: Mitochondria fuel astrocyte homeostatic support and neuroprotection

Cell Calcium

Verkhratsky, A.; Semyanov, A.

Note / Inclusive Brain: From Neuronal Doctrine to the Active Milieu

Function

Semyanov, A.; Verkhratsky, A.

Note / Astrocytes regulate action potential propagation in myelinated axons: It is very crowded at the node of Ranvier

Cell Calcium

Butt, A.M.; Verkhratsky, A.

Review / Microglia states and nomenclature: A field at its crossroads

Neuron

Paolicelli, R.C.; Sierra, A.; Stevens, B.; Tremblay, M.E.; Aguzzi, A.; Ajami, B.; Amit, I.; Audinat, E.; Bechmann, I.; Bennett, M.; Bennett, F.; Bessis, A.; Biber, K.; Bilbo, S.; Blurton-Jones, M.; Boddeke, E.; Brites, D.; Brône, B.; Brown, G.C.; Butovsky, O.; Carson, M.J.; Castellano, B.; Colonna, M.; Cowley, S.A.; Cunningham, C.; Davalos, D.; De Jager, P.L.; de Strooper, B.; Denes, A.; Eggen, B.J.L.; Eyo, U.; Galea, E.; Garel, S.; Ginhoux, F.; Glass, C.K.; Gokce, O.; Gomez-Nicola, D.; González, B.; Gordon, S.; Graeber, M.B.; Greenhalgh, A.D.; Gressens, P.; Greter, M.; Gutmann, D.H.; Haass, C.; Heneka, M.T.; Heppner, F.L.; Hong, S.; Hume, D.A.; Jung, S.; Kettenmann, H.; Kipnis, J.; Koyama, R.; Lemke, G.; Lynch, M.; Majewska, A.; Malcangio, M.; Malm, T.; Mancuso, R.; Masuda, T.; Matteoli, M.; McColl, B.W.; Miron, V.E.; Molofsky, A.V.; Monje, M.; Mracsko, E.; Nadjar, A.; Neher, J.J.; Neniskyte, U.; Neumann, H.; Noda, M.; Peng, B.; Peri, F.; Perry, V.H.; Popovich, P.G.; Pridans, C.; Priller, J.; Prinz, M.; Ragozzino, D.; Ransohoff, R.M.; Salter, M.W.; Schaefer, A.; Schafer, D.P.; Schwartz, M.; Simons, M.; Smith, C.J.; Streit, W.J.; Tay, T.L.; Tsai, L.H.; Verkhratsky, A.; von Bernhardi, R.; Wake, H.; Wittamer, V.; Wolf, S.A.; Wu, L.J.; Wyss-Coray, T.

Review / Evolution of neuroglia

Annals of the New York Academy of Sciences

Verkhratsky, A.; Arranz, A.M.; Ciuba, K.; Pękowska, A.

Review / Astrocyte energy and neurotransmitter metabolism in Alzheimer's disease: Integration of the glutamate/GABA-glutamine cycle

Progress in Neurobiology

Andersen, J.V.; Schousboe, A.; Verkhratsky, A.

Review / Glial decline and loss of homeostatic support rather than inflammation defines cognitive aging

Neural Regeneration Research

Verkhratsky, A.; Lazareva, N.; Semyanov, A.

2021

Book / Astrocytes in Psychiatric Disorders, Springer-Nature, (ISBN: 978-3-030-77375-5), pp. 377.

B. Li, V. Parpura, A. Verkhratsky & C. Scuderi

Article / Astrocyte arborization enhances Ca2+ but not cAMP signaling plasticity

GLIA

Pirnat, S.; Božić, M.; Dolanc, D.; Horvat, A.; Tavčar, P.; Vardjan, N.; Verkhratsky, A.; Zorec, R.; Stenovec, M.

Article / Iron induces two distinct Ca2+ signalling cascades in astrocytes

Communications Biology

Guan, W.; Xia, M.; Ji, M.; Chen, B.; Li, S.; Zhang, M.; Liang, S.; Chen, B.; Gong, W.; Dong, C.; Wen, G.; Zhan, X.; Zhang, D.; Li, X.; Zhou, Y.; Guan, D.; Verkhratsky, A.; Li, B.

Article / The anti-inflammatory astrocyte revealed: the role of the microbiome in shaping brain defences

Signal Transduction and Targeted Therapy

Verkhratsky, A.; Illes, P.; Tang, Y.; Semyanov, A.

Article / Systemic Inflammation and Astrocyte Reactivity in the Neuropsychiatric Sequelae of COVID-19: Focus on Autism Spectrum Disorders

Frontiers in Cellular Neuroscience

Valenza, M.; Steardo, L.; Steardo, L.; Verkhratsky, A.; Scuderi, C.

Article / Concentration-dependent duality of bFGF in regulation of barrier properties of human brain endothelial cells

Journal of Cellular Physiology

Kriaučiūnaitė, K.; Pociūtė, A.; Kaušylė, A.; Pajarskienė, J.; Verkhratsky, A.; Pivoriūnas, A.

Article / Astrocyte–Endotheliocyte Axis in the Regulation of the Blood–Brain Barrier

Neurochemical Research

Pivoriūnas, A.; Verkhratsky, A.

Article / Satellite Glial Cells and Astrocytes, a Comparative Review

Neurochemical Research

Hanani, M.; Verkhratsky, A.

Article / The Association Between Antidepressant Effect of SSRIs and Astrocytes: Conceptual Overview and Meta‐analysis of the Literature

Neurochemical Research

Chen, B.; Zhang, M.; Ji, M.; Gong, W.; Chen, B.; Zorec, R.; Stenovec, M.; Verkhratsky, A.; Li, B.

Article / Coming full circle: In vivo Veritas, or expanding the neuroscience frontier

Cell Calcium

Khiroug, L.; Verkhratsky, A.

Article / Caloric restriction modifies spatiotemporal calcium dynamics in mouse hippocampal astrocytes

Biochimica et Biophysica Acta - Molecular Cell Research

Denisov, P.; Popov, A.; Brazhe, A.; Lazareva, N.; Verkhratsky, A.; Semyanov, A.

Article / Connexins as therapeutic targets in neurological and neuropsychiatric disorders

Biochimica et Biophysica Acta - Molecular Basis of Disease

Charvériat, M.; Mouthon, F.; Rein, W.; Verkhratsky, A.

Article / Immortalised Hippocampal Astrocytes from 3xTG-AD Mice Fail to Support BBB Integrity In Vitro: Role of Extracellular Vesicles in Glial-Endothelial Communication

Cellular and Molecular Neurobiology

Kriaučiūnaitė, K.; Kaušylė, A.; Pajarskienė, J.; Tunaitis, V.; Lim, D.; Verkhratsky, A.; Pivoriūnas, A.

Article / Astrocyte dystrophy in ageing brain parallels impaired synaptic plasticity

Aging Cell

Popov, A.; Brazhe, A.; Denisov, P.; Sutyagina, O.; Li, L.; Lazareva, N.; Verkhratsky, A.; Semyanov, A.

Article / Snapshot of microglial physiological functions

Neurochemistry International

Verkhratsky, A.; Sun, D.; Tanaka, J.

Article / Astrocytes in heavy metal neurotoxicity and neurodegeneration

Brain Research

Li, B.; Xia, M.; Zorec, R.; Parpura, V.; Verkhratsky, A.

Article / The Safeguarding Microglia: Central Role for P2Y12 Receptors

Frontiers in Pharmacology

Lin, S.S.; Tang, Y.; Illes, P.; Verkhratsky, A.

Article / Mitochondrial Localization and Function of the Purinergic Receptor P2X7

Function

Kroemer, G.; Verkhratsky, A.

Article / Iatrogenic Iron Promotes Neurodegeneration and Activates Self-Protection of Neural Cells against Exogenous Iron Attacks

Function

Xia, M.; Liang, S.; Li, S.; Ji, M.; Chen, B.; Zhang, M.; Dong, C.; Chen, B.; Gong, W.; Wen, G.; Zhan, X.; Zhang, D.; Li, X.; Zhou, Y.; Guan, D.; Verkhratsky, A.; Li, B.

Article / Overexpression of α-Synuclein Reorganises Growth Factor Profile of Human Astrocytes

Molecular Neurobiology

Şengül, B.; Dursun, E.; Verkhratsky, A.; Gezen-Ak, D.

Editorial / Preface for the Vladimir Parpura Honorary Issue of Neurochemical Research

Neurochemical Research

Verkhratsky, A.; Schousboe, A.; Zorec, R.

Editorial / Post-COVID-19 neuropsychiatric syndrome: Is maladaptive glial recovery to blame?

Acta Physiologica

Steardo, L.; Steardo, L.; Verkhratsky, A.; Scuderi, C.

Editorial / Special issue editorial: Glial plasticity in health and disease

European Journal of Neuroscience

Majewska, A.K.; Verkhratsky, A.; Hughes, E.G.

Note / Systemic inflammation and neuronal hyperexcitability: Deciphering cellular neuropathology of sickness behaviour

Brain, Behavior, and Immunity

Lin, S.S.; Verkhratsky, A.

Note / Astrocyte-derived extracellular vesicles mediate intercellular communications of the neurogliovascular unit

Neural Regeneration Research

Pivoriūnas, A.; Verkhratsky, A.

Note / When day meets night: Subsiding calcium signalling translates daylight into new neurones

Cell Calcium

Verkhratsky, A.; Dayanithi, G.

Review / Lifestyle-dependent microglial plasticity: training the brain guardians

Biology Direct

Augusto-Oliveira, M.; Verkhratsky, A.

Review / Astrocytic processes: from tripartite synapses to the active milieu

Trends in Neurosciences

Semyanov, A.; Verkhratsky, A.

Review / Ca2+ handling at the mitochondria-ER contact sites in neurodegeneration

Cell Calcium

Lim, D.; Dematteis, G.; Tapella, L.; Genazzani, A.A.; Calì, T.; Brini, M.; Verkhratsky, A.

Review / Early evolutionary history (from bacteria to hemichordata) of the omnipresent purinergic signalling: A tribute to Geoff Burnstock inquisitive mind

Biochemical Pharmacology

Verkhratsky, A.

Review / Astroglial asthenia and loss of function, rather than reactivity, contribute to the ageing of the brain

Pflugers Archiv European Journal of Physiology

Verkhratsky, A.; Augusto-Oliveira, M.; Pivoriūnas, A.; Popov, A.; Brazhe, A.; Semyanov, A.

Review / Astrocytes in alzheimer’s disease: Pathological significance and molecular pathways

Cells

Preman, P.; Alfonso-Triguero, M.; Alberdi, E.; Verkhratsky, A.; Arranz, A.M.

Review / Reactive astrocyte nomenclature, definitions, and future directions

Nature Neuroscience

Escartin, C.; Galea, E.; Lakatos, A.; O’Callaghan, J.P.; Petzold, G.C.; Serrano-Pozo, A.; Steinhäuser, C.; Volterra, A.; Carmignoto, G.; Agarwal, A.; Allen, N.J.; Araque, A.; Barbeito, L.; Barzilai, A.; Bergles, D.E.; Bonvento, G.; Butt, A.M.; Chen, W.T.; Cohen-Salmon, M.; Cunningham, C.; Deneen, B.; De Strooper, B.; Díaz-Castro, B.; Farina, C.; Freeman, M.; Gallo, V.; Goldman, J.E.; Goldman, S.A.; Götz, M.; Gutiérrez, A.; Haydon, P.G.; Heiland, D.H.; Hol, E.M.; Holt, M.G.; Iino, M.; Kastanenka, K.V.; Kettenmann, H.; Khakh, B.S.; Koizumi, S.; Lee, C.J.; Liddelow, S.A.; MacVicar, B.A.; Magistretti, P.; Messing, A.; Mishra, A.; Molofsky, A.V.; Murai, K.K.; Norris, C.M.; Okada, S.; Oliet, S.H.R.; Oliveira, J.F.; Panatier, A.; Parpura, V.; Pekna, M.; Pekny, M.; Pellerin, L.; Perea, G.; Pérez-Nievas, B.G.; Pfrieger, F.W.; Poskanzer, K.E.; Quintana, F.J.; Ransohoff, R.M.; Riquelme-Perez, M.; Robel, S.; Rose, C.R.; Rothstein, J.D.; Rouach, N.; Rowitch, D.H.; Semyanov, A.; Sirko, S.; Sontheimer, H.; Swanson, R.A.; Vitorica, J.; Wanner, I.B.; Wood, L.B.; Wu, J.; Zheng, B.; Zimmer, E.R.; Zorec, R.; Sofroniew, M.V.; Verkhratsky, A.

Short Survey / Mens sana in corpore sano: Lifestyle changes modify astrocytes to contain Alzheimer's disease

Neural Regeneration Research

Augusto-Oliveira, M.; Verkhratsky, A.

2020

Article / Disruption of oligodendrocyte progenitor cells is an early sign of pathology in the triple transgenic mouse model of Alzheimer's disease

Neurobiology of Aging

Vanzulli, I.; Papanikolaou, M.; De-La-Rocha, I.C.; Pieropan, F.; Rivera, A.D.; Gomez-Nicola, D.; Verkhratsky, A.; Rodríguez, J.J.; Butt, A.M.

Article / Exocytosis of large-diameter lysosomes mediates interferon γ-induced relocation of MHC class II molecules toward the surface of astrocytes

Cellular and Molecular Life Sciences

Božić, M.; Verkhratsky, A.; Zorec, R.; Stenovec, M.

Article / Neuroinfection may contribute to pathophysiology and clinical manifestations of COVID-19

Acta Physiologica

Steardo, L.; Steardo, L.; Zorec, R.; Verkhratsky, A.

Article / Academia europaea position paper on translational medicine: The cycle model for translating scientific results into community benefits

Journal of Clinical Medicine

Hegyi, P.; Petersen, O.H.; Holgate, S.; Erőss, B.; Garami, A.; Szakács, Z.; Dobszai, D.; Balaskó, M.; Kemény, L.; Peng, S.; Monteiro, J.; Varró, A.; Lamont, T.; Laurence, J.; Gray, Z.; Pickles, A.; Fitzgerald, G.A.; Griffiths, C.E.M.; Jassem, J.; Rusakov, D.A.; Verkhratsky, A.; Szentesi, A.

Article / Multipurpose Na+ ions mediate excitation and cellular homeostasis: Evolution of the concept of Na+ pumps and Na+/Ca2+ exchangers

Cell Calcium

Blaustein, M.P.; Lariccia, V.; Khanashvili, D.; Annunziato, L.; Verkhratsky, A.

Article / Caloric restriction triggers morphofunctional remodeling of astrocytes and enhances synaptic plasticity in the mouse hippocampus

Cell Death and Disease

Popov, A.; Denisov, P.; Bychkov, M.; Brazhe, A.; Lyukmanova, E.; Shenkarev, Z.; Lazareva, N.; Verkhratsky, A.; Semyanov, A.

Article / On the special role of NCX in astrocytes: Translating Na+-transients into intracellular Ca2+ signals

Cell Calcium

Rose, C.R.; Ziemens, D.; Verkhratsky, A.

Article / Na+-dependent transporters: The backbone of astroglial homeostatic function

Cell Calcium

Verkhratsky, A.; Rose, C.R.

Article / NMDA Receptors in Astrocytes

Neurochemical Research

Verkhratsky, A.; Chvátal, A.

Editorial / Nestin regulates vesicular dynamics in proliferative reactive astrocyte

Acta Physiologica

Jorgačevski, J.; Verkhratsky, A.

Editorial / Editorial: Sleep and Mood Disorders

Frontiers in Psychiatry

Verkhratsky, A.; Nedergaard, M.; Steardo, L.; Li, B.

Letter / Iron Aggravates the Depressive Phenotype of Stressed Mice by Compromising the Glymphatic System

Neuroscience Bulletin

Liang, S.; Lu, Y.; Li, Z.; Li, S.; Chen, B.; Zhang, M.; Chen, B.; Ji, M.; Gong, W.; Xia, M.; Verkhratsky, A.; Wu, X.; Li, B.

Note / Untangling Complexities of Glial-Neuronal Communications: Astroglial Metabolic Cascades Orchestrate Tonic Inhibition in the Thalamus

Neuron

Verkhratsky, A.

Note / Large-Scale Proteomics Highlights Glial Role in Neurodegeneration

Cell Metabolism

Verkhratsky, A.; Zorec, R.

Review / Can COVID-19 pandemic boost the epidemic of neurodegenerative diseases?

Biology Direct

Verkhratsky, A.; Li, Q.; Melino, S.; Melino, G.; Shi, Y.

Review / Psychiatric face of COVID-19

Translational Psychiatry

Steardo, L.; Steardo, L.; Verkhratsky, A.

Review / Neuropathobiology of COVID-19: The Role for Glia

Frontiers in Cellular Neuroscience

Tremblay, M.E.; Madore, C.; Bordeleau, M.; Tian, L.; Verkhratsky, A.

Review / Astroglia-specific contributions to the regulation of synapses, cognition and behaviour

Neuroscience and Biobehavioral Reviews

Augusto-Oliveira, M.; Arrifano, G.P.; Takeda, P.Y.; Lopes-Araújo, A.; Santos-Sacramento, L.; Anthony, D.C.; Verkhratsky, A.; Crespo-Lopez, M.E.

Review / Astrocytes in rapid ketamine antidepressant action

Neuropharmacology

Stenovec, M.; Li, B.; Verkhratsky, A.; Zorec, R.

Review / Ionic signalling in astroglia beyond calcium

Journal of Physiology

Verkhratsky, A.; Untiet, V.; Rose, C.R.

Review / Pathological ATPergic Signaling in Major Depression and Bipolar Disorder

Frontiers in Molecular Neuroscience

Illes, P.; Verkhratsky, A.; Tang, Y.

Review / Astroglia in Sepsis Associated Encephalopathy

Neurochemical Research

Shulyatnikova, T.; Verkhratsky, A.

2019

Book / Neuroglia in Neurodegenerative Diseases

A. Verkhratsky, M. Ho, R. Zorec & V. Parpura

Book / Microglia: Methods and Protocols

O. Garaschuk & A. Verkhratsky

Article / Spontaneous BOLD waves – A ovel hemodynamic activity in Sprague-Dawley rat brain detected by FMRI.

Journal of Cerebral Blood Flow and Metabolism

A. Shatillo, A. Lipponen, R. A. Salo, H. Tanila, A. Verkhratsky, R. Giniatullin, O. H. Gröhn

Article / Astrocyte Specific Remodeling of Plasmalemmal Cholesterol Composition by Ketamine Indicates a New Mechanism of Antidepressant Action

Scientific Reports

Lasič, E.; Lisjak, M.; Horvat, A.; Božić, M.; Šakanović, A.; Anderluh, G.; Verkhratsky, A.; Vardjan, N.; Jorgačevski, J.; Stenovec, M.; Zorec, R.

Article / Astroglial calcium signaling in aging and alzheimer’s disease

Cold Spring Harbor Perspectives in Biology

Verkhratsky, A.

Article / Persistent Na + influx drives L-type channel resting Ca 2+ entry in rat melanotrophs

Cell Calcium

Kayano, T.; Sasaki, Y.; Kitamura, N.; Harayama, N.; Moriya, T.; Dayanithi, G.; Verkhratsky, A.; Shibuya, I.

Article / Calcium microdomain formation at the perisynaptic cradle due to NCX Reversal: A computational study

Frontiers in Cellular Neuroscience

Wade, J.J.; Breslin, K.; Wong-Lin, K.F.; Harkin, J.; Flanagan, B.; Van Zalinge, H.; Hall, S.; Dallas, M.; Bithell, A.; Verkhratsky, A.; McDaid, L.

Article / Leptin increases expression of 5-HT2B receptors in astrocytes thus enhancing action of fluoxetine on the depressive behavior induced by sleep deprivation

Frontiers in Psychiatry

Li, X.; Liang, S.; Li, Z.; Li, S.; Xia, M.; Verkhratsky, A.; Li, B.

Editorial / Editorial: Glia in health and disease

Frontiers in Molecular Neuroscience

Ho, M.S.; Verkhratsky, A.; Duan, S.; Parpura, V.

Editorial / Astroglial signalling in health and disease

Neuroscience Letters

Verkhratsky, A.; Zorec, R.

Editorial / Preface

Methods in Molecular Biology

Garaschuk, O.; Verkhratsky, A.

Note / Astroglial Ca2+ signals trigger pathological behaviour in optogenetic mouse

Cell Calcium

Verkhratsky, A.; Semyanov, A.

Review / Astroglial atrophy in Alzheimer’s disease

Pflugers Archiv European Journal of Physiology

Verkhratsky, A.; Rodrigues, J.J.; Pivoriunas, A.; Zorec, R.; Semyanov, A.

Review / Astrogliopathology in the infectious insults of the brain

Neuroscience Letters

Zorec, R.; Županc, T.A.; Verkhratsky, A.

Review / Sleep disturbance in bipolar disorder: Neuroglia and circadian rhythms

Frontiers in Psychiatry

Steardo, L.J.; De Filippis, R.; Carbone, E.A.; Segura-Garcia, C.; Verkhratsky, A.; De Fazio, P.

Review / Role of astrocytes, microglia, and tanycytes in brain control of systemic metabolism

Nature Neuroscience

García-Cáceres, C.; Balland, E.; Prevot, V.; Luquet, S.; Woods, S.C.; Koch, M.; Horvath, T.L.; Yi, C.X.; Chowen, J.A.; Verkhratsky, A.; Araque, A.; Bechmann, I.; Tschöp, M.H.

2018

Article / Neuroglia: Realising their true potential

Brain and Neuroscience Advances

A. Butt & A. Verkhratsky

Article / The History of the Decline and Fall of the Glial Numbers Legend.

Neuroglia

A. Verkhratsky & A. M. Butt

Article / The special case of human astrocytes.

Neuroglia

A.Verkhratsky, N. A. Oberheim-Bush, M. Nedergaard & A. Butt

Article / Early history of neuroglial research: Personalities

Neuroglia

A. Chvatal & A. Verkhratsky

Article / L-dopa and fluoxetine upregulate astroglial 5-HT2B receptors and ameliorate depression in Parkinson disease mice

Neuroglia

D. Song, K. Ma, A.Verkhratsky & L. Peng

Article / Remembering Ben Barres

Neuroglia

A.M. Butt, M. Nedergaard & A. Verkhratsky

Article / Loss of calretinin and parvalbumin positive interneurones in the hippocampal CA1 of aged Alzheimer's disease mice

Neuroscience Letters

Zallo, F.; Gardenal, E.; Verkhratsky, A.; Rodríguez, J.J.

Article / Neuroglia in the autistic brain: evidence from a preclinical model

Molecular Autism

Bronzuoli, M.R.; Facchinetti, R.; Ingrassia, D.; Sarvadio, M.; Schiavi, S.; Steardo, L.; Verkhratsky, A.; Trezza, V.; Scuderi, C.

Article / Vasopressin and oxytocin in sensory neurones: expression, exocytotic release and regulation by lactation

Scientific Reports

Dayanithi, G.; Forostyak, O.; Forostyak, S.; Kayano, T.; Ueta, Y.; Verkhratsky, A.

Article / Interstitial ion homeostasis and acid-base balance are maintained in oedematous brain of mice with acute toxic liver failure

Neurochemistry International

Obara-Michlewska, M.; Ding, F.; Popek, M.; Verkhratsky, A.; Nedergaard, M.; Zielinska, M.; Albrecht, J.

Article / Regulation of Glycogen Content in Astrocytes via Cav-1/PTEN/AKT/GSK-3β Pathway by Three Anti-bipolar Drugs

Neurochemical Research

Jia, S.; Li, B.; Huang, J.; Verkhratsky, A.; Peng, L.

Article / The ameliorative effect of fluoxetine on neuroinflammation induced by sleep deprivation

Journal of Neurochemistry

Xia, M.; Li, X.; Yang, L.; Ren, J.; Sun, G.; Qi, S.; Verkhratsky, A.; Li, B.

Article / Potassium and sodium microdomains in thin astroglial processes: A computational model study

PLoS Computational Biology

Breslin, K.; Wade, J.J.; Wong-Lin, K.F.; Harkin, J.; Flanagan, B.; Van Zalinge, H.; Hall, S.; Walker, M.; Verkhratsky, A.; McDaid, L.

Article / Physiology of astroglia

Physiological Reviews

Verkhratsky, A.; Nedergaard, M.

Editorial / Cell-autonomous astrocytopathy in Alzheimer's disease

Acta Physiologica

Verkhratsky, A.; Rodríguez, J.J.

Editorial / Editorial: Neuroglia molecular mechanisms in psychiatric disorders

Frontiers in Molecular Neuroscience

Scuderi, C.; Noda, M.; Verkhratsky, A.

Review / Preventing neurodegeneration by adrenergic astroglial excitation

FEBS Journal

Zorec, R.; Parpura, V.; Verkhratsky, A.

Review / The remembrance of the things past: Conserved signalling pathways link protozoa to mammalian nervous system

Cell Calcium

Plattner, H.; Verkhratsky, A.

Review / Astroglial 5-HT2B receptor in mood disorders

Expert Review of Neurotherapeutics

Peng, L.; Song, D.; Li, B.; Verkhratsky, A.

Review / Pathological human astroglia in Alzheimer's disease: Opening new horizons with stem cell technology

Future Neurology

Mohamet, L.; Jones, V.C.; Dayanithi, G.; Verkhratsky, A.

Review / Crosslink between calcium and sodium signalling

Experimental Physiology

Verkhratsky, A.; Trebak, M.; Perocchi, F.; Khananshvili, D.; Sekler, I.

Review / Astroglial vesicular network: evolutionary trends, physiology and pathophysiology

Acta Physiologica

Zorec, R.; Parpura, V.; Verkhratsky, A.

Review / Enteric glia regulate gut motility in health and disease

Brain Research Bulletin

Grubišić, V.; Verkhratsky, A.; Zorec, R.; Parpura, V.

2017

Chapter / Noradrenergic Signaling and Astroglia

R. Zorec & N. Vardjan

R. Zorec, N. Vardjan & A. Verkhratsky (2016): . In:

Chapter / Noradrenergic Signaling and Astroglia

R. Zorec & N. Vardjan

B. Li, D. Song, T. Du, A. Verkhratsky & L. Peng

Article / Crosslink of calcium and sodium signalling in health and disease

Experimental Physiology

A. Verkhratsky, M. Trebak, F. Perocchi, D. Khananishvili & I.Sekler

Article / Increased calcium-sensing receptor immunoreactivity in the hippocampus of a triple transgenic mouse model of Alzheimer's disease

Frontiers in Neuroscience

Gardenal, E.; Chiarini, A.; Armato, U.; Dal Prà, I.; Verkhratsky, A.; Rodríguez, J.J.

Article / Biphasic regulation of caveolin-1 gene expression by fluoxetine in astrocytes: Opposite effects of PI3K/AKT and MAPK/ERK signaling pathways on c-fos

Frontiers in Cellular Neuroscience

Li, B.; Jia, S.; Yue, T.; Yang, L.; Huang, C.; Verkhratsky, A.; Peng, L.

Article / Stratification of astrocytes in healthy and diseased brain

Brain Pathology

Verkhratsky, A.; Zorec, R.; Parpura, V.

Article / Bi-phasic regulation of glycogen content in astrocytes via Cav-1/PTEN/PI3K/AKT/GSK-3β pathway by fluoxetine

Psychopharmacology

Bai, Q.; Song, D.; Gu, L.; Verkhratsky, A.; Peng, L.

Article / Astrocytic face of Alzheimer's disease

Behavioural Brain Research

Zorec, R.; Parpura, V.; Vardjan, N.; Verkhratsky, A.

Article / Astroglial Vesicular Trafficking in Neurodegenerative Diseases

Neurochemical Research

Zorec, R.; Parpura, V.; Verkhratsky, A.

Article / Ammonium Increases TRPC1 Expression Via Cav-1/PTEN/AKT/GSK3β Pathway

Neurochemical Research

Wang, W.; Gu, L.; Verkhratsky, A.; Peng, L.

Article / Chronic treatment with anti-bipolar drugs down-regulates gene expression of TRPC1 in neurones

Frontiers in Cellular Neuroscience

Du, T.; Rong, Y.; Feng, R.; Verkhratsky, A.; Peng, L.

Article / Aberrant iPSC-derived human astrocytes in Alzheimer's disease

Cell Death and Disease

Jones, V.C.; Atkinson-Dell, R.; Verkhratsky, A.; Mohamet, L.

Article / Glutamate and ATP at the Interface Between Signaling and Metabolism in Astroglia: Examples from Pathology

Neurochemical Research

Parpura, V.; Fisher, E.S.; Lechleiter, J.D.; Schousboe, A.; Waagepetersen, H.S.; Brunet, S.; Baltan, S.; Verkhratsky, A.

Review / Astroglial calcium signalling in Alzheimer's disease

Biochemical and Biophysical Research Communications

Verkhratsky, A.; Rodríguez-Arellano, J.J.; Parpura, V.; Zorec, R.

Review / Astrocytic pathological calcium homeostasis and impaired vesicle trafficking in neurodegeneration

International Journal of Molecular Sciences

Vardjan, N.; Verkhratsky, A.; Zorec, R.

2016

Article / Complex and differential glial responses in Alzheimer s disease and ageing

Current Alzheimer research

J.J. Rodriguez, A.M. Butt, E. Gardenal, V. Parpura, A. Verkhratsky

Article / Calcium signalling toolkits in astrocytes and spatio-temporal progression of Alzheimer's disease

Current Alzheimer research

D. Lim, J.J. Rodriguez-Arellano, V. Parpura, R. Zorec, F. Zeidan-Chulia, A.A. Genazzani, A. Verkhratsky

Article / Astrocytic vesicles and gliotransmitters: Slowness of vesicular release and synaptobrevin2-laden vesicle nanoarchitecture

Neuroscience

Zorec, R.; Verkhratsky, A.; Rodríguez, J.J.; Parpura, V.

Article / Calcium signalling toolkits in astrocytes and spatio-temporal progression of alzheimer’s disease

Current Alzheimer Research

Lim, D.; Rodríguez-Arellano, J.J.; Parpura, V.; Zorec, R.; Zeidán-Chuliá, F.; Genazzani, A.A.; Verkhratsky, A.

Article / Expression of familial Alzheimer disease presenilin 1 gene attenuates vesicle traffic and reduces peptide secretion in cultured astrocytes devoid of pathologic tissue environment

GLIA

Stenovec, M.; Trkov, S.; Lasič, E.; Terzieva, S.; Kreft, M.; Rodríguez Arellano, J.J.; Parpura, V.; Verkhratsky, A.; Zorec, R.

Article / Inseparable tandem: Evolution chooses atp and ca2+ to control life, death and cellular signalling

Philosophical Transactions of the Royal Society B: Biological Sciences

Plattner, H.; Verkhratsky, A.

Article / Up-Regulation of Oligodendrocyte Lineage Markers in the Cerebellum of Autistic Patients: Evidence from Network Analysis of Gene Expression

Molecular Neurobiology

Zeidán-Chuliá, F.; de Oliveira, B.H.N.; Casanova, M.F.; Casanova, E.L.; Noda, M.; Salmina, A.B.; Verkhratsky, A.

Article / Physiology of spontaneous [Ca2+]i oscillations in the isolated vasopressin and oxytocin neurones of the rat supraoptic nucleus

Cell Calcium

Kortus, S.; Srinivasan, C.; Forostyak, O.; Ueta, Y.; Sykova, E.; Chvatal, A.; Zapotocky, M.; Verkhratsky, A.; Dayanithi, G.

Article / Sodium-calcium exchanger and R-type Ca2+ channels mediate spontaneous [Ca2+]i oscillations in magnocellular neurones of the rat supraoptic nucleus

Cell Calcium

Kortus, S.; Srinivasan, C.; Forostyak, O.; Zapotocky, M.; Ueta, Y.; Sykova, E.; Chvatal, A.; Verkhratsky, A.; Dayanithi, G.

Article / Specific profiles of ion channels and ionotropic receptors define adipose- and bone marrow derived stromal cells

Stem Cell Research

Forostyak, O.; Butenko, O.; Anderova, M.; Forostyak, S.; Sykova, E.; Verkhratsky, A.; Dayanithi, G.

Article / Astrogliopathology in neurological, neurodevelopmental and psychiatric disorders

Neurobiology of Disease

Verkhratsky, A.; Parpura, V.

Editorial / Calcium signalling in stem cells: Molecular physiology and multiple roles

Cell Calcium

Dayanithi, G.; Verkhratsky, A.

Review / Astrocytes in physiological aging and Alzheimer's disease

Neuroscience

Rodríguez-Arellano, J.J.; Parpura, V.; Zorec, R.; Verkhratsky, A.

Review / Complex and differential glial responses in alzheimer´s disease and ageing

Current Alzheimer Research

Rodríguez, J.J.; Butt, A.M.; Gardenal, E.; Parpura, V.; Verkhratsky, A.

Review / Astroglia dynamics in ageing and Alzheimer's disease

Current Opinion in Pharmacology

Verkhratsky, A.; Zorec, R.; Rodríguez, J.J.; Parpura, V.

Review / Principles of sodium homeostasis and sodium signalling in astroglia

GLIA

Rose, C.R.; Verkhratsky, A.

Review / Translational potential of astrocytes in brain disorders

Progress in Neurobiology

Verkhratsky, A.; Steardo, L.; Parpura, V.; Montana, V.

Review / The homeostatic astroglia emerges from evolutionary specialization of neural cells

Philosophical Transactions of the Royal Society B: Biological Sciences

Verkhratsky, A.; Nedergaard, M.

Review / Targeting astrocytes in bipolar disorder

Expert Review of Neurotherapeutics

Peng, L.; Li, B.; Verkhratsky, A.

Review / Purinergic neurone-glia signalling in cognitive-related pathologies

Neuropharmacology

Illes, P.; Verkhratsky, A.

Review / Physiology of Ca2+ signalling in stem cells of different origins and differentiation stages

Cell Calcium

Forostyak, O.; Forostyak, S.; Kortus, S.; Sykova, E.; Verkhratsky, A.; Dayanithi, G.

Review / Astrocytes: a central element in neurological diseases

Acta Neuropathologica

Pekny, M.; Pekna, M.; Messing, A.; Steinhäuser, C.; Lee, J.M.; Parpura, V.; Hol, E.M.; Sofroniew, M.V.; Verkhratsky, A.

Review / Astrocytes as secretory cells of the central nervous system: Idiosyncrasies of vesicular secretion

EMBO Journal

Verkhratsky, A.; Matteoli, M.; Parpura, V.; Mothet, J.P.; Zorec, R.

2015

Book / Physiology of Astroglia: Channels, Receptors, Transporters, Ion Signaling and Gliotransmission,

A. Verkhratsky & V. Parpura

Article / Microglial response to Alzheimer’s disease is differentially modulated by voluntary wheel running and enriched environments

Brain Structure and Function

Rodríguez, J.J.; Noristani, H.N.; Verkhratsky, A.

Article / Memory formation shaped by astroglia

Frontiers in Integrative Neuroscience

Zorec, R.; Horvat, A.; Vardjan, N.; Verkhratsky, A.

Article / Decrease of gene expression of astrocytic 5-HT2B receptors parallels development of depressive phenotype in a mouse model of Parkinson’s disease

Frontiers in Cellular Neuroscience

Zhang, X.; Song, D.; Gu, L.; Ren, Y.; Verkhratsky, A.; Peng, L.

Article / Crosstalk between MAPK/ERK and PI3K/AKT signal pathways during brain ischemia/reperfusion

ASN Neuro

Zhou, J.; Du, T.; Li, B.; Rong, Y.; Verkhratsky, A.; Peng, L.

Article / Cell type-specific in vivo expression of genes encoding signalling molecules in the brain in response to chronic mild stress and chronic treatment with fluoxetine

Psychopharmacology

Dong, L.; Li, B.; Verkhratsky, A.; Peng, L.

Article / Ammonium increases Ca2+ signalling and upregulates expression of Cav1.2 gene in astrocytes in primary cultures and in the in vivo brain

Acta Physiologica

Wang, F.; Du, T.; Liang, C.; Verkhratsky, A.; Peng, L.

Article / Chronic treatment with anti-bipolar drugs suppresses glutamate release from astroglial cultures

Amino Acids

Liu, Z.; Song, D.; Yan, E.; Verkhratsky, A.; Peng, L.

Article / Fluoxetine induces alkalinization of astroglial cytosol through stimulation of sodium-hydrogen exchanger 1: Dissection of intracellular signaling pathways

Frontiers in Cellular Neuroscience

Ren, J.; Song, D.; Bai, Q.; Verkhratsky, A.; Peng, L.

Article / Full-length transient receptor potential vanilloid 1 channels mediate calcium signals and possibly contribute to osmoreception in vasopressin neurones in the rat supraoptic nucleus

Cell Calcium

Moriya, T.; Shibasaki, R.; Kayano, T.; Takebuchi, N.; Ichimura, M.; Kitamura, N.; Asano, A.; Hosaka, Y.Z.; Forostyak, O.; Verkhratsky, A.; Dayanithi, G.; Shibuya, I.

Editorial / Evolution of calcium signalling

Cell Calcium

Plattner, H.; Verkhratsky, A.

Letter / Rho GTPase RAC1 at the Molecular Interface Between Genetic and Environmental Factors of Autism Spectrum Disorders

NeuroMolecular Medicine

Zeidán-Chuliá, F.; Salmina, A.B.; Noda, M.; Verkhratsky, A.

Review / Glial Asthenia and Functional Paralysis: A New Perspective on Neurodegeneration and Alzheimers Disease

Neuroscientist

Verkhratsky, A.; Marutle, A.; Rodríguez-Arellano, J.J.; Nordberg, A.

Review / Targeting astrocytes in major depression

Expert Review of Neurotherapeutics

Peng, L.; Verkhratsky, A.; Gu, L.; Li, B.

Review / Neuroinflammation in Alzheimer's disease

The Lancet Neurology

Heneka, M.T.; Carson, M.J.; Khoury, J.E.; Landreth, G.E.; Brosseron, F.; Feinstein, D.L.; Jacobs, A.H.; Wyss-Coray, T.; Vitorica, J.; Ransohoff, R.M.; Herrup, K.; Frautschy, S.A.; Finsen, B.; Brown, G.C.; Verkhratsky, A.; Yamanaka, K.; Koistinaho, J.; Latz, E.; Halle, A.; Petzold, G.C.; Town, T.; Morgan, D.; Shinohara, M.L.; Perry, V.H.; Holmes, C.; Bazan, N.G.; Brooks, D.J.; Hunot, S.; Joseph, B.; Deigendesch, N.; Garaschuk, O.; Boddeke, E.; Dinarello, C.A.; Breitner, J.C.; Cole, G.M.; Golenbock, D.T.; Kummer, M.P.

Review / The ancient roots of calcium signalling evolutionary tree

Cell Calcium

Plattner, H.; Verkhratsky, A.

Review / Why are Astrocytes Important?

Neurochemical Research

Verkhratsky, A.; Nedergaard, M.; Hertz, L.

Review / Pathologic potential of astrocytic vesicle traffic: New targets to treat neurologic diseases?

Cell Transplantation

Vardjan, N.; Verkhratsky, A.; Zorec, R.

2014

Book / Glutamate and ATP at interface of metabolism and signalling.

V. Parpura, A. Schousboe & A. Verkhratsky

V. Parpura, A. Schousboe & A. Verkhratsky (Eds)

Book / Introduction to Neuroglia. In: Colloquium Series on Neuroglia in Biology and Medicine: From Physiology to Disease

A. Verkhratsky & V. Parpura

Article / Astrogliopathology: A central element of neuropsychiatric diseases?

Neuroscientist

Verkhratsky, A.; Rodríguez, J.J.; Steardo, L.

Article / Retinal macroglia changes in a triple transgenic mouse model of Alzheimer's disease

Experimental Eye Research

Edwards, M.M.; Rodríguez, J.J.; Gutierrez-Lanza, R.; Yates, J.; Verkhratsky, A.; Lutty, G.A.

Article / Complex and region-specific changes in astroglial markers in the aging brain

Neurobiology of Aging

Rodríguez, J.J.; Yeh, C.Y.; Terzieva, S.; Olabarria, M.; Kulijewicz-Nawrot, M.; Verkhratsky, A.

Article / Astroglial cradle in the life of the synapse

Philosophical Transactions of the Royal Society B: Biological Sciences

Verkhratsky, A.; Nedergaard, M.

Article / Ammonium increases Ca2+ signalling and up-regulates expression of TRPC1 gene in astrocytes in primary cultures and in the in vivo brain

Neurochemical Research

Liang, C.; Du, T.; Zhou, J.; Verkhratsky, A.; Peng, L.

Article / TRP channels coordinate ion signalling in astroglia

Reviews of Physiology, Biochemistry and Pharmacology

Verkhratsky, A.; Reyes, R.C.; Parpura, V.

Article / Pathological role for exocytotic glutamate release from astrocytes in hepatic encephalopathy

Current Neuropharmacology

Montana, V.; Verkhratsky, A.; Parpura, V.

Article / History of electrophysiology and the patch clamp

Methods in Molecular Biology

Verkhratsky, A.; Parpura, V.

Article / Glial calcium signalling in Alzheimer’s disease

Reviews of Physiology, Biochemistry and Pharmacology

Lim, D.; Ronco, V.; Grolla, A.A.; Verkhratsky, A.; Genazzani, A.A.

Article / Altered expression of Alzheimer's disease-related genes in the cerebellum of autistic patients: a model for disrupted brain connectome and therapy.

Cell death & disease

Zeidán-Chuliá, F.; de Oliveira, B.H.N.; Salmina, A.B.; Casanova, M.F.; Gelain, D.P.; Noda, M.; Verkhratsky, A.; Moreira, J.C.

Article / Neurological and psychiatric disorders as a neuroglial failure

Periodicum Biologorum

Verkhratsky, A.; Parpura, V.

Article / Biology of purinergic signalling: Its ancient evolutionary roots, its omnipresence and its multiple functional significance

BioEssays

Verkhratsky, A.; Burnstock, G.

Article / Differential deregulation of astrocytic calcium signalling by amyloid-β, TNFα, IL-1β and LPS

Cell Calcium

Ronco, V.; Grolla, A.A.; Glasnov, T.N.; Canonico, P.L.; Verkhratsky, A.; Genazzani, A.A.; Lim, D.

Editorial / Neuroglia as a central element of neurological diseases: An underappreciated target for therapeutic intervention

Current Neuropharmacology

Peng, L.; Parpura, V.; Verkhratsky, A.

Review / Neuroglia in ageing and disease

Cell and Tissue Research

Verkhratsky, A.; Rodríguez, J.J.; Parpura, V.

Review / Calcium signalling in sensory neurones and peripheral glia in the context of diabetic neuropathies

Cell Calcium

Verkhratsky, A.; Fernyhough, P.

Review / Probing astroglia with carbon nanotubes: Modulation of form and function

Philosophical Transactions of the Royal Society B: Biological Sciences

Gottipati, M.K.; Verkhratsky, A.; Parpura, V.

Review / Glia in the pathogenesis of neurodegenerative diseases

Biochemical Society Transactions

Verkhratsky, A.; Parpura, V.; Pekna, M.; Pekny, M.; Sofroniew, M.

Review / Calcium signalling and calcium channels: Evolution and general principles

European Journal of Pharmacology

Verkhratsky, A.; Parpura, V.

Review / Caenorhabditis elegans glia modulate neuronal activity and behavior

Frontiers in Cellular Neuroscience

Stout, R.F.; Verkhratsky, A.; Parpura, V.

Review / Store-operated calcium entry in neuroglia

Neuroscience Bulletin

Verkhratsky, A.; Parpura, V.

Review / The glial perspective of autism spectrum disorders

Neuroscience and Biobehavioral Reviews

Zeidán-Chuliá, F.; Salmina, A.B.; Malinovskaya, N.A.; Noda, M.; Verkhratsky, A.; Moreira, J.C.F.

2013

Chapter / Neuroglia

H. Kettenmann & B.R.Ransom

A. Verkhratsky, V. Parpura

Chapter / Neuroglia

H. Kettenmann, B.R.Ransom

M. Noda, A. Verkhratsky

Article / Complex and region specific changes in astroglial markers in the ageing brain.

Neurobiology of Aging

J. J. Rodríguez, C.Y. Yeh, S. Terzieva, M. Olabarria, M. Kulijewicz-Nawrot & A. Verkhratsky

Article / Astrocytes and glutamate homeostasis in Alzheimer’s disease: a decrease in glutamine synthetase but not in glutamate transporter-1 in the prefrontal cortex

ASN Neuro

M. Kulijewicz-Nawrot, E. Syková, A. Chvátal, A. Verkhratsky and J. J. Rodríguez

Article / Glutamine synthetase in astrocytes from entorhinal cortex of the triple transgenic animal model of Alzheimer's disease is not affected by pathological progression

Biogerontology

Yeh, C.Y.; Verkhratsky, A.; Terzieva, S.; Rodríguez, J.J.

Article / Cognitive recovery and restoration of cell proliferation in the dentate gyrus in the 5XFAD transgenic mice model of Alzheimer's disease following 2-hydroxy-DHA treatment

Biogerontology

Fiol-Deroque, M.A.; Gutierrez-Lanza, R.; Terés, S.; Torres, M.; Barceló, P.; Rial, R.V.; Verkhratsky, A.; Escribá, P.V.; Busquets, X.; Rodríguez, J.J.

Article / Astrocytes and glutamate homoeostasis in Alzheimer's disease: A decrease in glutamine synthetase, but not in glutamate transporter-1, in the prefrontal cortex

ASN Neuro

Kulijewicz-Nawrot, M.; Syková, E.; Chvátal, A.; Verkhratsky, A.; Rodríguez, J.J.

Article / Increased densities of resting and activated microglia in the dentate gyrus follow senile plaque formation in the CA1 subfield of the hippocampus in the triple transgenic model of Alzheimer's disease

Neuroscience Letters

Rodríguez, J.J.; Noristani, H.N.; Hilditch, T.; Olabarria, M.; Yeh, C.Y.; Witton, J.; Verkhratsky, A.

Article / Amyloid-b and Alzheimer's disease type pathology differentially affects the calcium signalling toolkit in astrocytes from different brain regions

Cell Death and Disease

Grolla, A.A.; Sim, J.A.; Lim, D.; Rodriguez, J.J.; Genazzani, A.A.; Verkhratsky, A.

Article / Ca2+ signalling early in evolution - all but primitive

Journal of Cell Science

Plattner, H.; Verkhratsky, A.

Article / TRPC1-mediated Ca2+ and Na+ signalling in astroglia: Differential filtering of extracellular cations

Cell Calcium

Reyes, R.C.; Verkhratsky, A.; Parpura, V.

Letter / Enriched environment and physical activity reverse astrogliodegeneration in the hippocampus of AD transgenic mice

Cell Death and Disease

Rodríguez, J.J.; Terzieva, S.; Olabarria, M.; Lanza, R.G.; Verkhratsky, A.

Review / Astroglia in neurological diseases

Future Neurology

Verkhratsky, A.; Rodríguez, J.J.; Parpura, V.

Review / Astrogliopathology: Could nanotechnology restore aberrant calcium signalling and pathological astroglial remodelling?

Biochimica et Biophysica Acta - Molecular Cell Research

Parpura, V.; Verkhratsky, A.

Review / Microglia: New Roles for the Synaptic Stripper

Neuron

Kettenmann, H.; Kirchhoff, F.; Verkhratsky, A.

2012

Book / Purinergic Signalling in the Nervous System

G. Burnstock, A. Verkhratsky

Chapter / Neuroscience in the 21st Century

D.W.Pfaff

H. Kettenmann & A. Verkhratsky

Chapter / Gap Junctions in the Nervous System: Physiological and Pathological Roles

E.Dere

A. Verkhratsky & V. Parpura

Chapter / Research Progress in Alzheimer's Disease and Dementia

Miao-Kun Sun

J. J. Rodríguez & A. Verkhratsky

Article / High tryptophan diet reduces CA1 intraneuronal β-amyloid in the triple transgenic mouse model of Alzheimer's disease

Aging Cell

Noristani, H.N.; Verkhratsky, A.; Rodríguez, J.J.

Article / Astrocytic cytoskeletal atrophy in the medial prefrontal cortex of a triple transgenic mouse model of Alzheimer's disease

Journal of Anatomy

Kulijewicz-Nawrot, M.; Verkhratsky, A.; Chvátal, A.; Syková, E.; Rodríguez, J.J.

Article / The astrocyte excitability brief: From receptors to gliotransmission

Neurochemistry International

Parpura, V.; Verkhratsky, A.

Article / Neuroglia at the crossroads of homoeostasis, metabolism and signalling: Evolution of the concept

ASN Neuro

Parpura, V.; Verkhratsky, A.

Article / Astroglial excitability and gliotransmission: An appraisal of Ca2+ as a signalling route

ASN Neuro

Zorec, R.; Araque, A.; Carmignoto, G.; Haydon, P.G.; Verkhratsky, A.; Parpura, V.

Article / Plasmalemmal Na+/Ca2+ exchanger modulates Ca2+-dependent exocytotic release of glutamate from rat cortical astrocytes

ASN Neuro

Reyes, R.C.; Verkhratsky, A.; Parpura, V.

Review / Neurotransmitters and integration in neuronal-astroglial networks

Neurochemical Research

Verkhratsky, A.; Rodríguez, J.J.; Parpura, V.

Review / The serotonergic system in ageing and Alzheimer's disease

Progress in Neurobiology

Rodríguez, J.J.; Noristani, H.N.; Verkhratsky, A.

Review / Neurological diseases as primary gliopathies: A reassessment of neurocentrism

ASN Neuro

Verkhratsky, A.; Sofroniew, M.V.; Messing, A.; deLanerollei, N.C.; Rempe, D.; Rodríguez, J.J.; Nedergaard, M.

Review / Calcium signalling in astroglia

Molecular and Cellular Endocrinology

Verkhratsky, A.; Rodríguez, J.J.; Parpura, V.

Review / Astrocytes revisited: Concise historic outlook on glutamate homeostasis and signaling

Croatian Medical Journal

Parpura, V.; Verkhratsky, A.

Review / Homeostatic function of astrocytes: Ca2+ and Na+ signaling

Translational Neuroscience

Parpura, V.; Verkhratsky, A.

Review / Sodium dynamics: Another key to astroglial excitability?

Trends in Neurosciences

Kirischuk, S.; Parpura, V.; Verkhratsky, A.

Review / P2X receptor-mediated synaptic transmission

Wiley Interdisciplinary Reviews: Membrane Transport and Signaling

Lalo, U.; Verkhratsky, A.; Burnstock, G.; Pankratov, Y.

Review / Glial cells in (patho)physiology

Journal of Neurochemistry

Parpura, V.; Heneka, M.T.; Montana, V.; Oliet, S.H.R.; Schousboe, A.; Haydon, P.G.; Stout, R.F.; Spray, D.C.; Reichenbach, A.; Pannicke, T.; Pekny, M.; Pekna, M.; Zorec, R.; Verkhratsky, A.

Review / P2X receptors in neuroglia

Wiley Interdisciplinary Reviews: Membrane Transport and Signaling

Verkhratsky, A.; Pankratov, Y.; Lalo, U.; Nedergaard, M.

2011

Chapter / Astrocytes: Wiring the Brain

E. Schemes, D.C. Spray

J. J. Rodríguez, C. Matute, A. Verkhratsky

Article / Early astrocytic atrophy in the entorhinal cortex of a triple transgenic animal model of Alzheimer's disease

ASN Neuro

Yeh, C.Y.; Vadhwana, B.; Verkhratsky, A.; Rodríguez, J.J.

Article / Voluntary running and environmental enrichment restores impaired hippocampal neurogenesis in a triple transgenic mouse model of Alzheimer's disease

Current Alzheimer Research

Rodríguez, J.J.; Noristani, H.N.; Olabarria, M.; Fletcher, J.; Somerville, T.D.D.; Yeh, C.Y.; Verkhratsky, A.

Article / Increased hippocampal CA1 density of serotonergic terminals in a triple transgenic mouse model of Alzheimer's disease: An ultrastructural study

Cell Death and Disease

Noristani, H.N.; Meadows, R.S.; Olabarria, M.; Verkhratsky, A.; Rodríguez, J.J.

Article / Age-dependent decrease in glutamine synthetase expression in the hippocampal astroglia of the triple transgenic Alzheimer's disease mouse model: Mechanism for deficient glutamatergic transmission?

Molecular Neurodegeneration

Olabarria, M.; Noristani, H.N.; Verkhratsky, A.; Rodríguez, J.J.

Review / Neurogenesis in Alzheimer's disease

Journal of Anatomy

Rodríguez, J.J.; Verkhratsky, A.

Review / Where the thoughts dwell: The physiology of neuronal-glial "diffuse neural net"

Brain Research Reviews

Verkhratsky, A.; Parpura, V.; Rodríguez, J.J.

Review / Neuroglial roots of neurodegenerative diseases?

Molecular Neurobiology

Rodríguez, J.J.; Verkhratsky, A.

Review / Ca2+ sources for the exocytotic release of glutamate from astrocytes

Biochimica et Biophysica Acta - Molecular Cell Research

Parpura, V.; Grubišic, V.; Verkhratsky, A.

2010

Book / Calcium imaging in neurobiology.

A. Verkhratsky & O.H.Petersen

Article / Astrocytes in Alzheimer's Disease

Neurotherapeutics

Verkhratsky, A.; Olabarria, M.; Noristani, H.N.; Yeh, C.Y.; Rodriguez, J.J.

Article / Serotonin fibre sprouting and increase in serotonin transporter immunoreactivity in the CA1 area of hippocampus in a triple transgenic mouse model of Alzheimer's disease

European Journal of Neuroscience

Noristani, H.N.; Olabarria, M.; Verkhratsky, A.; Rodríguez, J.J.

Article / Concomitant astroglial atrophy and astrogliosis in a triple transgenic animal model of Alzheimer's disease

GLIA

Olabarria, M.; Noristani, H.N.; Verkhratsky, A.; Rodríguez, J.J.

Article / Increase in the density of resting microglia precedes neuritic plaque formation and microglial activation in a transgenic model of Alzheimer's disease

Cell Death and Disease

Rodríguez, J.J.; Witton, J.; Olabarria, M.; Noristani, H.N.; Verkhratsky, A.

Review / Neuroglia in neurodegeneration

Brain Research Reviews

Heneka, M.T.; Rodríguez, J.J.; Verkhratsky, A.

Review / Glial calcium and diseases of the nervous system

Cell Calcium

Nedergaard, M.; Rodríguez, J.J.; Verkhratsky, A.

Review / Recent advances in (patho)physiology of astroglia

Acta Pharmacologica Sinica

Verkhratsky, A.; Parpura, V.

Short Survey / The Achilles heel of γ-secretase: Can we contain Alzheimer's disease by reducing synthesis of β-amyloid?

Acta Pharmacologica Sinica

Verkhratsky, A.; Rodríguez, J.J.

2021

Elected member of the Polish Academy of Arts and Sciences, Polska Akademia Umiej?tno?ci.

2019

Honorary Professor of China Medical University, Shenyang, China

Elected Corresponding Member of Slovenian Academy of Sciences and Arts

Honorary Professor and Chair, Chairman of the Academic Committee of the Key Laboratory of Sichuan Province for Acupuncture & Chronobiology, Chengdu University of Traditional Chinese Medicine, Chengdu, China

2018

Distinguished Professor of Chengdu University of Traditional Chinese Medicine, Chengdu, China

Distinguished professor of Jinan Unibersity, Guangzhou, China

2017

Elected member of Polish National Academy of Sciences

2016

Vice-Presidnet and Chairmen of the Class C (Life Science and Medicine) of the Academia Europaea

Copernicus Visiting Professor at the University of Ferrara

2013

Dozor Visiting Scholar award, Ben Gurion University, Beer Sheva, Israel

Fellow of Japan Society for the Promotion of Science

Elected member of Nationale Akademie der Wissenschaften Leopoldina (The German National Academy of Sciences Leopoldina).

2012

Elected member of Real Academia Nacional de Farmacia, Spain

Research Award of German Purine Club

Elected member of European Dana Alliance for the Brain Initiatives (since 2015 Dana Alliance for Brain Initiatives).

2006

Chairman of the Physiology and Medicine Section of the Academia Europaea; Member of the Council

2005

Elected Member of Academia Europaea

2022

Invited talk | Challenging “inflammageing” of the brain: glial paralysis, rather than reactivity defines brain ageing

Alzheimer’s Research UK Conference - Invited talk

A. Verkhratsky

Invited talk | Physiology of astrocytes

Neuronus IBRO Neuroscience Forum - Invited talk

A.Verkhratsky

Invited talk | Neuroglia in health and disease: from Golgi and Lugaro to modern days

72nd Nationall Congress of Italian Physiological society - Invited talk

A.Verkhratsky

Invited talk | Glial paralysis, rather than reactivity defines brain ageing and opens the gates for neurodegeneration

Israel Society for Neuroscieence (ISFN) annual meeting - Invited talk

A.Verkhratsky

Invited talk | Astroglial signalling in ageing and AD

European Calcium Society meeting 2022 - Invited talk

A. Verkhratsky

Invited talk | Glial paralysis defines brain ageing

International meeting "Synapses under stress: Early events induced by metabolic failure at glutamatergic synapses" - Invited talk

A. Verkhratsky

2021

Invited talk | Astroglia in ageing

XVII International Congress of Medical Biology and Genetics - Invited talk

A. Verkhratsky

Invited talk | Principles of astrogliopathology

Purines 2021: Xth Meeting of the Brazilian Purine Club - Invited talk

A. Verkhratsky

Invited talk | Astrocytes in ageing dna neurodegneeration

Meeting of Korean Soceity of Neuroscience - Invited talk

A. Verkhratsky

Invited talk | Principles of astrogliopathology

Achucarro Internatoonal Glial School (online), ; - Invited talk

A. Verkhratsky

Invited talk | The impact of astrocyte-centered views on neurology.

The COST Action TrainingSchool; New technological tools for the study of cytoplasmic intermediate filaments in the central nervous system in health and disease (online), - Invited talk

A. Verkhratsky

Invited talk | Principles of astrogliopathology

8th European (virtual) Congress of Pharmacology (EPHAR 2021) - Invited talk

A. Verkhratsky

Invited talk | Evolution of the Nervous System: Why Translation from Animal Models of Neurological Disorders Failed

Semmelweis Symposium - Invited talk

A. Verkhratsky

Invited talk | Challenging 'inflammageing' of the brain: glial paralysis, rather than reactivity defines brain ageing

Institute of Basic Science Conference on Brain Science (online). "Functional interplay between Neurones and Glia", , - Invited talk

A. Verkhratsky

Invited talk | Glial decline defines brain ageing

VII International Conference of Lithuanian Association of Stem Cells Researchers, - Invited talk

A. Verkhratsky

Invited talk | Astrocyte iron homeostasis: links to astrogliosis and neurodegeneration

71st SIF National Congress of The Italian Society of Physiology (online), - Invited talk

A.Verkhratsky

Invited talk | History of neuroscience

KUST Global Mentoring Conference (online), - Invited talk

A. Verkhratsky

Invited talk | Astrocyte iron homeostasis: links to astrogliosis and neurodegeneration

1st China-Japan-Korea Neuroscience Meeting (online) - Invited talk

A. Verkhratsky

Invited talk | Role of Glia and Neuroinflammation in the Neuropsychiatric and Neurological Aspects of COVID-19

IBRO Global Neuroscience Webinar Series, "Neuroscience & COVUD-19 - Invited talk

A. Verkhratsky

Invited talk | Mens sana in corpore sano: Lifestyle changes modify astrocytes to prolong cognitive longevity

International School "Neurodegeneration beyond Amyloid and Tau - Invited talk

A. Verkhratsky

2020

Invited talk | Astroglia evolution, physiology and pathophysiology

3rd International Symposium on Physiology and Pathology of Neuroglia, Mexico - Invited talk

Alexei Verkhratsky

Invited talk | Reactive astrocytes in neuropathology”

IV International Conference of Lithuanian Association of Stem Cell Researchers (online), Vilnius, Lithuania. - Invited talk

Alexei Verkhratsky

Invited talk | Astrocytes: Indispensable Neuronal Supporters in Sickness and in Health

International Webinar of the Americn Physiological Socity “The Brain as a Whole: Executive Neurons and Sustaining Homeostatic Glia” - Invited talk

Alexei Verkhratsky

Invited talk | Principles of astrogliopathology with an emphasis on astrocytes in Alzheimer’s disease

FENS Forum 2020 (online) The Satellite Symposium “The role of glial cells in the era of personalised mediine”, Glasgo, July 15. - Invited talk

Alexei Verkhratsky

Invited talk | Astroglia in Neuropsychiatric Disorders

4th Turkish Neuroendocrinology Congress (online); Istanbul, Turkey. - Invited talk

Alexei Verkhratsky

2019

Invited talk | Principles of astrogliopathology: From reactivity to atrophy and degeneration

23rd Biennal Meeting of the European Socuety for Neurochemistry - Invited talk

A. Verkhratsky

Invited talk | Principles of astrogliopathology

17th Turkish Neuroscience Congress - Invited talk

A Verkhratsky

Invited talk | Neuroglia: Functional paralysis and reactivity in Neurodegenertive pathologies

XIV Congress of Italian Society for Neurology - Invited talk

A. Verkhratsky

Invited talk | Glial physiology, pathology and homeostasis

The 13th Biennial Conference of Chinese Neuroscience Society - Invited talk

A Verkhratsky

Invited talk | Principles of astrogliopathology

International conference “Functions of Neuroglia” in commemoration of Alexander Roitbak 100th birthday - Invited talk

A Verkhratsky

Invited talk | Ionic excitability of astrocytes (beyond calcium)

10th IBRO World Congress of Neuroscience - Invited talk

A Verkhratsky

Invited talk | Astroglia define plasticity responses in the diseased brain

ASN-ISN Congress - Invited talk

A Verkhratsky

Invited talk | Pathological plasticity of astroglia

XIV European Meeting on Glial Cells in Health and Disease - Invited talk

A Verkhratsky

2018

Invited talk | Principles of astrogliopathology

International conference “More than neurons: Toward a less neurocentric view of brain disorders” - Invited talk

A Verkhratsky

Invited talk | Physiology and pathophysiology of astroglia

Sino-German Summer School “Frontiers in Purinergic Signalling and Acupuncture” - Invited talk

A Verkhratsky

Invited talk | Principles of astrogliopathology: From reactivity to atrophy

: British Pharmacological Society annual meeting - Invited talk

A Verkhratsky

Invited talk | Astrocytes in Alzheimer's disease: human stem cells open new research frontiers

Annual meeting of the Lithuanian Association of Stem Cells Researchers - Invited talk

A Verkhratsky

Invited talk | Astroglia define plasticity of the diseased brain

The 43rd FEBS Congress, - Invited talk

A Verkhratsky

Invited talk | Redefining neurone-centrism in neurological disorders: Principles of astrogliopathology

International conference “Frontiers in Life and Natural Sciences”, - Invited talk

A Verkhratsky

Invited talk | Redefining neurono-centrism: Principle of astrogliopathology

International conference “Physiology and Pathophysiology 2018: Molecules, Cells, Organs and Systems” - Invited talk

A Verkhratsky

Invited talk | Historical and evolutionary perspectives of fluid flow in CNS

International conference “Moving the Brain Fluids Glymphatic System and Beyond” - Invited talk

A Verkhratsky

2017

Invited talk | Astroglia in cognitive disorders: do human iPSCS-derived cells hold the key?

International conference “Stem Cells: Translational research”, - Invited talk

A Verkhratsky

Invited talk | Redefining neuron-centrism: Principles of astrogliopathology

2nd Sino-German Symposium on Purinergic Signaling, Pain and Acupuncture - Invited talk

A Verkhratsky

Invited talk | Principles of astrogliopathology and astrocytes in Alzheimer's disease

2nd meeting of Baltic Physiological Societies - Invited talk

A Verkhratsky

Invited talk | Pathological plasticity of astroglia: From reactivity to astrodegeneration

The 69th Natioal Congress of the Italian Physiological Society - Invited talk

A Verkhratsky

Invited talk | Emergence and evolution of calcium signalling system

20th International Symposium on Calcium Binding Proteins and Calcium Function in Health and Disease (CaBP20) - Invited talk

A Verkhratsky

Invited talk | Ionic signalling and astroglial function

Joint Meeting of the Federation of European Physiological Societies and the Austrian Physiological Society - Invited talk

A Verkhratsky

Invited talk | Complex and differential glial responses in Alzheimer's disease and ageing

6th Mediterranian Neuroscience Society Conference - Invited talk

A Verkhratsky

Invited talk | Molecular understanding of the function of astrocytes and their network in healthy and aging brain

International training school "Reactive gliosis - from mechanobiology and signal transduction to molecular targets and disease pathogenesis" - Invited talk

A Verkhratsky

2016

Invited talk | Glial calcium in health and disease

The Nobel forum meeting on - Invited talk

A. Verkhratsky

Invited talk | Reassessing neurocentrism: Principles of astrogliopathology

22nd Conference of the Society on NeuroImmune Pharmacology (SNIP) - Invited talk

A. Verkhratsky

Invited talk | Ionic signalling in astroglia

Joint Meeting of the Federation of European Physiological Societies (FEPS) and the French Physiological Society - Invited talk

A. Verkhratsky

Invited talk | ATP and calcium: the inseparable tandem chosen by evolution

The Royal Society meeting - Invited talk

A. Verkhratsky

Invited talk | Sodium signalling controls homeostatic cascades in astrocytes

The 12th International conference on Brain Energy and Metabolism - Invited talk

A. Verkhratsky

2015

Invited talk | Astroglial networks in health and disease: New Frontiers

69th National Congress of Italian Society for Anatomy and Histology - Invited talk

A. Verkhratsky

Invited talk | Astrocytes in healthy and diseased brain

Sheffield Glia Symposium - Invited talk

A. Verkhratsky

Invited talk | Neuroglia as a fulcrum for morbid changes: Redefining cellular neuropathology

Cardiff-Leuven Calcium Signalling Workshop - Invited talk

A. Verkhratsky

Invited talk | Principles of astrogliopathology

13th Meeting of the Neuroscience Society of Turkey - Invited talk

A. Verkhratsky

Invited talk | Na+ signalling and Na+ dependent homeostatic pathways in astroglia

The 7th International Conference on Na+/Ca2+ Exchange - Invited talk

A. Verkhratsky

Invited talk | Introduction into glial physiology and pathophysiology

IBRO-Kemali School in Neuroscience 2015 "Cannabinoid function in synapses, circuits and brain: from molecules to disease mechanisms" - Invited talk

A. Verkhratsky

Invited talk | Principles of Neurogliopathology

Academia Europae Research Conference "Ion channels trimming the brain" - Invited talk

A. Verkhratsky

Invited talk | Neurological and psychiatric disorders as gliopathies

Joint Meeting of the Federation of European Physiological Societies (FEPS) and the Baltic Physiological Societies - Invited talk

A. Verkhratsky

Invited talk | Astroglia in ageing and neurodegeneration with an emphasis on Alzheimer disease

Satellite meeting "Understanding the function of glia in the healthy and diseased CMS" in conjunction with the 25th Biennial meeting of the International Society for Neurochemistry - Invited talk

A. Verkhratsky

Invited talk | Sodium signalling in astroglia: role for ion channels and transporters

9th World Congress of International Brain Research Organization, Mini-Symposium 12 "Ionic transporters in microglia, astrocytes and oligodendrocytes: potential therapeutic targets for stroke" chaired by Lucio Annunziato & Marc Simard - Invited talk

A. Verkhratsky

Invited talk | The stress responses and homeostatic mechanisms in CNS diseases

European Research Conference "Intermediate Filaments (Nanofilaments) in Health and Disease". - Invited talk

A. Verkhratsky

Invited talk | Astrocytes as obligatory partners in purinergic and glutamatergic neurotransmission

46th Annual meeting of the American Society for Neurochemistry - Invited talk

A. Verkhratsky

Invited talk | Astroglial reparation as a way to brain longevity

4th CaribeGLIA Symposium "Glial Interactions and Brain Experiments” - Invited talk

A. Verkhratsky

2014

Invited talk | Astrocyte networks

"Brain networks – challenges and perspectives", BMFZ Meeting at Düsseldorf - Invited talk

A. Verkhratsky

Invited talk | Astrogliopathology: a central element of neurodegenerative and neuropsychiatric diseases

"Astrocytes in Health and Neurodegenerative Disease". A joint Biochemical Society / British Neuroscience Association Focused Meeting. - Invited talk

A. Verkhratsky

Invited talk | Astrocytes ER Ca2+ signalling and its pathological relevance

12th International Symposium “Molecular Basis of Pathology and Therapy in Neurological Disorders”, - Invited talk

A. Verkhratsky

Invited talk | Sodium signalling in astroglia

: Joint meeting of FEPS and Hungarian Physiological Society - Invited talk

A. Verkhratsky

Invited talk | Astroglia in Alzheimer disease

International symposium “Basic and translational neurochemistry: Glia and neurones in health and disease" - Invited talk

A. Verkhratsky

Invited talk | Neuroglia: central element of brain homeostasis and fulcrum of neuropsychiatric diseases

XVIII Congresso nazionale della Societa Italiana di Neuropsicofarmacologia - Invited talk

A. Verkhratsky

Invited talk | P2X and NMDA receptors mediate fast sodium signalling in astroglia

International conference "Glutamate/GABA and neuro-glia-vascular interplay in norm and pathology - Invited talk

A. Verkhratsky

Invited talk | Astroglia in Alzheimer's disease

4th Annual Gladstone/DZNE Workshop "Cell and Organ Interactions in the Pathogenesis of Neurodegenerative Diseases" - Invited talk

A. Verkhratsky

Invited talk | Neuron-glia interactions in health and disease: what we know and would like to know

International Research Conference "Astrocyte Intermediate Filaments (Nanofilaments) and Astrocyte Function in Health and Disease" - Invited talk

A. Verkhratsky

2013

Conference Paper | Calcium influx through reversed NCX controls migration of microglia

Advances in Experimental Medicine and Biology - Conference Paper

Noda, M.; Ifuku, M.; Mori, Y.; Verkhratsky, A.

Conference Paper | Sodium fluxes and astroglial function

Advances in Experimental Medicine and Biology - Conference Paper

Verkhratsky, A.; Noda, M.; Parpura, V.; Kirischuk, S.