Andreas Seifert

Ikerbasque Research Professor, CIC nanoGUNE

Group leader in Nanoengineering at CIC nanoGUNE.

Research line:

Nanoengineering, Biomedical Microsystems.

Rudolf Kingslake Medal and Prize (2013); Carl Zeiss Innovation Award (2006); Fellow as ‘Young innovator’, German federal state Baden-Württemberg (1998-2000).

Previous research experience in optical industry at Carl Zeiss (Germany) for EUV lithography, synchrotron & space optics, x-ray metrology and as group leader at the University of Freiburg (Germany) in micro-optics, biomedical microsystems, cardiovascular monitoring.

Doctor in Physics (1997) from University of Freiburg, Germany.

2024

Article / Temperature-Modulated Reversible Clustering of Gold Nanorods Driven by Small Surface Ligands

Chemistry - A European Journal

Kruse, J.; Rao, A.; Sánchez-Iglesias, A.; Montaño-Priede, J.L.; Iturrospe Ibarra, A.; Lopez, E.; Seifert, A.; Arbe, A.; Grzelczak, M.

Article / Evidence of internalized microplastics in mussel tissues detected by volumetric Raman imaging

Science of the Total Environment

Aramendia, J.; García-Velasco, N.; Amigo, J.M.; Izagirre, U.; Seifert, A.; Soto, M.; Castro, K.

Article / Amplifying Sensing Capabilities: Combining Plasmonic Resonances and Fresnel Reflections through Multivariate Analysis

Small Methods

Etxebarria-Elezgarai, J.; Bergamini, L.; Lopez, E.; Morant-Miñana, M.C.; Adam, J.; Zabala, N.; Aizpurua, J.; Seifert, A.

Article / Toward sub-second solution exchange dynamics in flow reactors for liquid-phase transmission electron microscopy

Nature Communications

Merkens, S.; Tollan, C.; De Salvo, G.; Bejtka, K.; Fontana, M.; Chiodoni, A.; Kruse, J.; Iriarte-Alonso, M.A.; Grzelczak, M.; Seifert, A.; Chuvilin, A.

Article / Power of Light: Raman Spectroscopy and Machine Learning for the Detection of Lung Cancer

ACS Omega

Hano, H.; Lawrie, C.H.; Suarez, B.; Paredes Lario, A.; Elejoste Echeverría, I.; Gómez Mediavilla, J.; Crespo Cruz, M.I.; Lopez, E.; Seifert, A.

Article / Unlocking Preclinical Alzheimer’s: A Multi-Year Label-Free In Vitro Raman Spectroscopy Study Empowered by Chemometrics

International Journal of Molecular Sciences

Lopez, E.; Etxebarria-Elezgarai, J.; García-Sebastián, M.; Altuna, M.; Ecay-Torres, M.; Estanga, A.; Tainta, M.; López, C.; Martínez-Lage, P.; Amigo, J.M.; Seifert, A.

Article / Fusion of Raman and FTIR Spectroscopy Data Uncovers Physiological Changes Associated with Lung Cancer

International Journal of Molecular Sciences

Hano, H.; Suarez, B.; Lawrie, C.H.; Seifert, A.

2023

Article / Light-Driven Self-Oscillation of Thermoplasmonic Nanocolloids

Advanced Materials

Mezzasalma, S.A.; Kruse, J.; Merkens, S.; Lopez, E.; Seifert, A.; Morandotti, R.; Grzelczak, M.

Article / Misinterpretation in microplastic detection in biological tissues: When 2D imaging is not enough

Science of the Total Environment

Benito-Kaesbach, A.; Amigo, J.M.; Izagirre, U.; Garcia-Velasco, N.; Arévalo, L.; Seifert, A.; Castro, K.

Article / Generalization of Self-Assembly Toward Differently Shaped Colloidal Nanoparticles for Plasmonic Superlattices

Small Methods

Charconnet, M.; Korsa, M.T.; Petersen, S.; Plou, J.; Hanske, C.; Adam, J.; Seifert, A.

Article / Photonic Technology for In Vivo Monitoring of Hypoxia–Ischemia

Advanced Science

Olaetxea, I.; Lafuente, H.; Lopez, E.; Izeta, A.; Jaunarena, I.; Seifert, A.

Review / The importance of choosing a proper validation strategy in predictive models. A tutorial with real examples

Analytica Chimica Acta

Lopez, E.; Etxebarria-Elezgarai, J.; Amigo, J.M.; Seifert, A.

2022

Article / Design and Development of a Bimodal Optical Instrument for Simultaneous Vibrational Spectroscopy Measurements

International Journal of Molecular Sciences

Arévalo, L.A.; O’brien, S.A.; Lopez, E.; Singh, G.P.; Seifert, A.

Article / Identification of Hypoxia-Ischemia by Chemometrics Considering Systemic Changes of Physiology

IEEE Journal of Biomedical and Health Informatics

Lafuente, H.; Olaetxea, I.; Valero, A.; Alvarez, F.J.; Izeta, A.; Jaunarena, I.; Seifert, A.

Review / Towards multi-molecular surface-enhanced infrared absorption using metal plasmonics

Nanoscale Horizons

Wagner, M.; Seifert, A.; Liz-Marzán, L.M.

2021

Article / Paradigms to assess the human health risks of nano- and microplastics

Microplastics and Nanoplastics

Seta Noventa, Matthew S. P. Boyles, Andreas Seifert, Simone Belluco, Aracaeli Sánchez Jiménez, Helinor J. Johnston, Lang Tran, Teresa F. Fernandes, Lapo Mughini-Gras, Massimiliano Orsini, Fabiana Corami, Kepa Castro, Franco Mutinelli, Massimo Boldrin, Victor Puntes, Mahshid Sotoudeh, Giulia Mascarello, Barbara Tiozzo, Polly McLean, Francesca Ronchi, Andy M. Booth, Albert A. Koelmans & Carmen Losasso

Article / Mechanically Tunable Lattice-Plasmon Resonances by Templated Self-Assembled Superlattices for Multi-Wavelength Surface-Enhanced Raman Spectroscopy

Small Methods

Charconnet, M.; Kuttner, C.; Plou, J.; García-Pomar, J.L.; Mihi, A.; Liz-Marzán, L.M.; Seifert, A.

Article / Rapid detection of thermal treatment of honey by chemometrics-assisted ftir spectroscopy

Foods

Antonova, O.; Calvo, J.; Seifert, A.

2020

Article / Gaussian Beam Shaping and Multivariate Analysis in Plasmonic Sensing

Analytical Chemistry

Etxebarria-Elezgarai, J.; Mowat, M.; Lopez, E.; Rodríguez, C.; Olaetxea, I.; Seifert, A.

Article / Machine Learning-Assisted Raman Spectroscopy for pH and Lactate Sensing in Body Fluids

Analytical Chemistry

Olaetxea, I.; Valero, A.; Lopez, E.; Lafuente, H.; Izeta, A.; Jaunarena, I.; Seifert, A.

Article / Evaluation of a biocompatible sealant for on-demand repair of vascular defects-a chronic study in a large animal model

Interactive Cardiovascular and Thoracic Surgery

Wussler, D.; Kiefer, S.; Naumann, S.; Hackner, D.; Nadjiri, J.; Meckel, S.; Haberstroh, J.; Kubicki, R.; Seifert, A.; Siepe, M.; Ewert, P.; Stiller, B.; Lang, N.

2019

Article / Heat generation by branched Au/Pd nanocrystals: Influence of morphology and composition

Nanoscale

Quintanilla, M.; Kuttner, C.; Smith, J.D.; Seifert, A.; Skrabalak, S.E.; Liz-Marzán, L.M.

2018

Article / Imidazole-Grafted Nanogels for the Fabrication of Organic–Inorganic Protein Hybrids

Advanced Functional Materials

Rodriguez-Abetxuko, A.; Morant-Miñana, M.C.; López-Gallego, F.; Yate, L.; Seifert, A.; Knez, M.; Beloqui, A.

2020

Improved plasmonic sensing by Gaussian beam shaping and nanostructured noble metal surfaces

Universidad Autónoma de Madrid

2018

Detection of hypoxia by the measurement of pH and lactate in blood by Raman spectroscopy

University of Navarra

Nanostructured transducers for enhanced plasmonic biosensing

University of the Basque Country

2019

Best Paper Award: M. Charconnet, C. Kuttner, C. Matricardi, A. Mihi, L.M. Liz-Marzán, A. Seifert, "Tunable plasmonics by self-assembled stretchable superlattices on macroscopic scale", International Conference on Optical MEMS and Nanophotonics (OMN), 2019, Daejeon, South Korea

2018

Best Poster Award: M. Charconnet, C. Hanske, C. Matricardi, A. Mihi, A. Seifert, and L. Liz-Marzán, “Universal self-assembly process of differently shaped nanoparticles,” International Workshop on Self-assembly and Hierarchical Materials in Biomedicine, 2018, San Sebastián, Spain

2024

Conference paper | Multivariate design and data analysis for plasmonic sensing

M. T. Korsa, J. Etxebarria-Elezgarai, U. F. S. Roggero, H. E. Hernández-Figueroa, J. Adam, and A. Seifert

Conference paper | Unveiling cell-to-cell evolution by Raman micro-spectroscopy

C.-C. Schubbe, J. Plou, A. Seifert, and E. Barth

Conference paper | Surface-enhanced Raman spectroscopy for early detection of Alzheimer’s disease

J. Etxebarria-Elezgarai, E. Lopez, M. García-Sebastián, M. Altuna, M. Ecay- Torres, A. Estanga, M. Tainta, C. López, P. Martínez-Lage, and A. Seifert

Conference paper | Plasmonic nanoantennas for biosensing and monitoring of cell activity

2024 International Conference on Optical MEMS and Nanophotonics (OMN) - Conference paper

U. F. S. Roggero, M. Zapata-Herrera, A. García-Etxarri, A. Seifert, and H. E. Hernández-Figueroa

Conference paper | Degenerate frequencies create sensing patterns for single-pixel imaging

M. Abedi and A. Seifert

Conference paper | Raman spectroscopy detects biochemical signatures in non-small cell lung cancer

H. Hano, B. Suarez, C. H. Lawrie, and A. Seifert

Conference Paper | Raman Spectroscopy Detects Biochemical Signatures in Non-Small Cell Lung Cancer

International Conference on Optical MEMS and Nanophotonics - Conference Paper

Hano, H.; Suarez, B.; Lawrie, C.H.; Seifert, A.

Conference Paper | Degenerate Frequencies Create Sensing Patterns for Single-Pixel Imaging

International Conference on Optical MEMS and Nanophotonics - Conference Paper

Abedi, M.; Seifert, A.

Conference Paper | Plasmonic nanoantennas for biosensing and monitoring of cell activity

International Conference on Optical MEMS and Nanophotonics - Conference Paper

Roggero, U.F.S.; Zapata-Herrera, M.; Garcia-Etxarri, A.; Seifert, A.; Hernandez-Figueroa, H.E.

Conference Paper | Surface-Enhanced Raman Spectroscopy for Early Detection of Alzheimer's Disease

International Conference on Optical MEMS and Nanophotonics - Conference Paper

Etxebarria-Elezgarai, J.; Lopez, E.; Garcia-Sebastian, M.; Altuna, M.; Ecay-Torres, M.; Estanga, A.; Tainta, M.; Lopez, C.; Martinez-Lage, P.; Seifert, A.

Invited talk | Multivariate design and data analysis for plasmonic sensing

SPIE Photonics West OPTO: Smart Photonic and Optoelectronic Integrated Circuits 2024 - Invited talk

M. T. Korsa, J. Etxebarria-Elezgarai, U. F. S. Roggero, H. E. Hernández-Figueroa, J. Adam, and A. Seifert

Oral presentation | CAR T therapy monitored by Raman spectroscopy: temporal trajectories of therapeutic response

ETPN2024 – European Technology Platform Nanomedicine - Oral presentation

J. Plou, C. H. Lawrie, and A. Seifert

Oral presentation | Early detection of Alzheimer’s disease using microscopy images of human dried blood plasma

ETPN2024 – European Technology Platform Nanomedicine - Oral presentation

M. Abedi and A. Seifert

Oral presentation | Analyzing human plasma by Raman spectroscopy at 532 nm: Role of carotenoids in human disease study

International Conference on Raman Spec- troscopy – ICORS XXVIII - Oral presentation

J. Aramendia, E. Lopez, G. Gorla, J. Etxebarria-Elezgarai, J. M. Amigo, K. Castro, and A. Seifert

Poster presentation | Non-invasive lung cancer detection by multivariate analysis of vibrational spectroscopy data

ETPN2024 – European Technology Platform Nanomedicine - Poster presentation

H. Hano, B. Suarez, C. H. Lawrie, and A. Seifert

Poster presentation | Customized augmentation framework for microscopy biofluid images

ETPN2024 – European Technology Platform Nanomedicine - Poster presentation

M. Abedi and A. Seifert

Poster presentation | Alzheimer’s disease classification by artificial intelligence using microscopy images of dried human body fluids

KES-InMed-24 – International KES Conference on Innovation in Medicine and Healthcare - Poster presentation

J. Bóbeda, J. Etxebarria-Elezgarai, L. V. Perez-Herrera, M. J. García-González, E. Alonso, M. García-Sebastián, M. Altuna, M. Ecay-Torres, A. Estanga, M. Tainta, C. López, E. Lopez, P. Martínez-Lage, A. Seifert, and K. López-Linares

Poster presentation | Monitoring cell line evolution via Raman spectroscopy and machine learning

nternational Conference on Spectral Imaging – IASIM-2024 - Poster presentation

C.-C. Schubbe, J. Plou, E. Barth, and A. Seifert

Poster presentation | Alzheimer’s classification via hyperspectral Raman imaging on specific zones of dried biofluids

International Conference on Spectral Imaging – IASIM-2024 - Poster presentation

E. Lopez, G. Gorla, J. Etxebarria-Elezgarai, J. Aramendia, K. Castro, A. Seifert, and J. M. Amigo

2023

Conference Paper | Plasmonic Signals Modified by Dielectric Layers and Exploited by Multivariate Analysis

International Conference on Optical MEMS and Nanophotonics - Conference Paper

Etxebarria-Elezgarai, J.; Bergamini, L.; Lopez Corrillero, E.; Morant-Minana, M.C.; Adam, J.; Seifert, A.

Conference Paper | Pigtailed Polymeric Optical Biosensor based on Interferometric Multimode Waveguide and Image Processing

International Conference on Optical MEMS and Nanophotonics - Conference Paper

Roggero, U.F.S.; Fernandez, J.R.; Seifert, A.; Hernandez-Figueroa, H.E.

Invited talk | Analysis of complex biological samples with confocal raman imaging and chemometrics. a case study: Microplastics in tissues

EuroAnalysis XXI - Invited talk

J. Aramendia, N. García-Velasco, J. M. Amigo, U. Izaguirre, A. Seifert, M. Soto, and K. Castro

Invited talk | Colliodal versus substrate-based plasmonic materials

2023 International Conference on Optical MEMS and Nanophotonics (OMN) and SBFoton International Optics and Photonics Conference (SBFoton IOPC) - Invited talk

Andreas Seifert

Oral presentation | First evidence of microplastics translocation in mussel tissues using raman imaging and chemometrics

Colloquium Chemiometricum Mediterraneum (CCM XI 2023) - Oral presentation

J. Aramendia, N. García-Velasco, J. M. Amigo, U. Izagirre, A. Seifert, L. Arévalo, M. Soto, and K. Castro

Oral presentation | Pigtailed polymeric optical biosensor based on interferometric multimode waveguide and image processing

2023 International Conference on Optical MEMS and Nanophotonics (OMN) and SBFoton International Optics and Photonics Conference (SBFoton IOPC) - Oral presentation

U. F. S. Roggero, J. R. Fernández, A. Seifert, and H. E. Hernández-Figueroa

Oral presentation | Plasmonic signals modified by dielectric layers and exploited by multivariate analysis

2023 International Conference on Optical MEMS and Nanophotonics (OMN) and SBFoton International Optics and Photonics Conference (SBFoton IOPC) - Oral presentation

J. Etxebarria-Elezgarai, L. Bergamini, E. L. Corrillero, M. C. Morant-Miñana, J. Adam, and A. Seifert

Poster presentation | Systematic assessment of feature selection methods with PLS-DA model for photonic in vitro detection of lung cancer

EuroAnalysis XXI - Poster presentation

H. Hano and A. Seifert

Poster presentation | Proper validation of classifica- tion models. a real-life example

Colloquium Chemiometricum Mediterraneum (CCM XI 2023) - Poster presentation

E. Lopez, J. M. Amigo, J. Etxebarria-Elezgarai, and A. Seifert

Poster presentation | Comparison of classification models for lung cancer detection using Raman spectroscopy

Colloquium Chemiometricum Mediterraneum (CCM XI 2023) - Poster presentation

H. Hano and A. Seifert

2022

Conference Paper | Highly selective, compact and efficient vertical in-coupling for interferometric optical biosensors

Journal of Physics: Conference Series - Conference Paper

Roggero, U.F.S.; Rubio-Noriega, R.E.; Seifert, A.; Hernández-Figueroa, H.E.

Conference Paper | Detection of Alzheimer's by Machine Learning-assisted Vibrational Spectroscopy in Human Cerebrospinal Fluid

Journal of Physics: Conference Series - Conference Paper

Arévalo, L.A.; Antonova, O.; O'Brien, S.A.; Singh, G.P.; Seifert, A.

Conference Paper | Drying Patterns of Cerebrospinal Fluid as Indicator for Alzheimer's Disease by a Machine Learning Framework

Journal of Physics: Conference Series - Conference Paper

Arévalo, L.A.; O'Brien, S.A.; Antonova, O.; Seifert, A.

Conference Paper | Bimodal Vibrational Spectroscopy for Simultaneously Operating Raman and FTIR

2022 Conference on Lasers and Electro-Optics Pacific Rim, CLEO-PR 2022 - Proceedings - Conference Paper

Arévalo, L.; O'Brien, S.; Lopez, E.; Bastida, A.; Singh, G.P.; Seifert, A.

Invited talk | Plasmonic superlattices

20th anniversary of CINSaT – Center for Interdisciplinary Nanostructure Science and Technology - Invited talk

Andreas Seifert

Oral presentation | Bimodal vibrational spectroscopy for simultaneously operating Raman and FTIR

ODF’22 – International Conference on Optics-Photonics Design and Fabrication - Oral presentation

L. A. Arévalo, S. A. O’Brien, E. Lopez, A. Bastida, G. P. Singh, and A. Seifert

Oral presentation | Drying patterns of cerebrospinal fluid as indica- tor for Alzheimer’s disease by a machine learning framework

ETPN2022 – European Technology Platform Nanomedicine - Oral presentation

L. A. Arévalo, S. A. O’Brien, A. Seifert

Oral presentation | Detection of Alzheimer’s disease by machine learning-assisted vibrational spectroscopy in cerebrospinal fluid

ETPN2022 – European Technology Platform Nanomedicine - Oral presentation

L. A. Arévalo, O. Antonova, S. A. O’Brien, A. Seifert

Oral presentation | Combination of plasmonic and dielectric properties by multivariate analysis for enhanced sensing

E-MRS European Materials Research Society, Spring Meeting - Oral presentation

J. Etxebarria-Elezgarai, L. Bergamini, E. Lopez, J. Adam, N. Zabala, J. Aizpurua, A. Seifert

Poster presentation | Improving anti-PD1 immunotherapy through targeting the HIF/hypoxia axis of clear cell renal cell carcinoma

ASEICA International Congress – Asociación Española de Investigación sobre el Cáncer - Poster presentation

M. Márquez López, E. Arnaitz González, C. Solé Cañadas, B. Suárez Álvarez, M. Armesto Álvarez, A. Seifert, C. Lawrie

2021

Invited talk | Plasmonic superlattices

E-MRS European Materials Research Society, 2019 Fall Meeting - Invited talk

A. Seifert

Oral presentation | Nanostructured noble metal surfaces and multivariate analysis for enhanced plasmonic sensing

12th International Conference on Optics-photonics Design & Fabrication - ODF’20 - Oral presentation

J. Etxebarria-Elezgarai, M. Mowat, L. Bergamini, N. Zabala, J. Aizpurua, and A. Seifert

Oral presentation | Regular self-assembled plasmonic nanoparticle superlattices: Characterization, modelling and applications

2021 Virtual MRS Spring Meeting & Exhibit - Oral presentation

M. Charconnet, M. T. Korsa, S. Petersen, L. M. Liz-Marzán, J. Adam, and A. Seifert

Oral presentation | Optimization of self- assembled plasmonic nanoparticle cluster lattices on a substrate

E-MRS European Materials Research Society, Fall Meeting - Oral presentation

M. T. Korsa, M. Charconnet, S. Petersen, A. Seifert, J. Adam

2020

Oral presentation | Photonic monitoring of perinatal asphyxia

Annual meeting ETPN2020 – European Technology Platform Nanomedicine - Oral presentation

I. Olaetxea, A. García, and A. Seifert

Oral presentation | Fabrication and optical characterization of gold NP superlattices

Nanoplus - Oral presentation

M. Charconnet, A. Seifert, and L. M. Liz-Marzán

2019

Conference Paper | Tunable Plasmonics by Self-Assembled Stretchable Superlattices on Macroscopic Scale

International Conference on Optical MEMS and Nanophotonics - Conference Paper

Charconnet, M.; Kuttner, C.; Matricardi, C.; Mihi, A.; Liz-Marzan, L.M.; Seifert, A.

Conference Paper | Determination of physiological lactate and pH by Raman spectroscopy

Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS - Conference Paper

Olaetxea, I.; Lopez, E.; Valero, A.; Seifert, A.

Conference Paper | Improved plasmonic resonance by Gaussian beam shaping

International Conference on Optical MEMS and Nanophotonics - Conference Paper

Etxebarria-Elezgarai, J.; Molinuevo, C.R.; Carmen, M.E.D.; Corrillero, E.L.; Azkarate-Askatsua, I.O.; Morant-Minana, M.C.; Seifert, A.

Invited talk | New pathways in plasmonic sensing

E-MRS European Materials Research Society, 2019 Fall Meeting - Invited talk

A. Seifert

Oral presentation | Fabrication, optical characterization and modelling of plasmonic superlattices

E-MRS European Materials Research Society, 2019 Fall Meeting - Oral presentation

M. Charconnet, C. Matricardi, A. Mihi, J. Adam, L. M. Liz-Marzán, and A. Seifert

Poster presentation | Optical characterization of plasmonic supercrystals

XXXVII Reunión Bienal de la Real Sociedad Española de Química - Poster presentation

M. Charconnet, J. Plou, I. Garcia, C. Matricardi, A. Mihi, L. M. Liz-Marzán, A. Seifert

Poster presentation | Innovative products based on photonics & bionanotechnology

EuroNanoForum 2019, Nanotechnology and Advanced Materials Progress under Horizon2020 and beyond - Poster presentation

A. Valero, A. Seifert

2018

Invited talk | Photonics for medical diagnostics: From the lab to the market

EuroSciCon NANOTECH & NANOBIOTECHNOLOGY - Invited talk

Andreas Seifert

Invited talk | Basque Nanoscience

6th Nano-Carbon Enhanced Materials Consortium (NCEM-6) - Invited talk

Andreas Seifert

Poster presentation | Cosolvent-assisted assembly of nanoparticles into highly regular plasmonic arrays

ImagineNano 2018 - Poster presentation

M. Charconnet, M.C. Morant-Miñana, C. Hanske, C. Matricardi, A. Mihi, A. Seifert, L.M. Liz-Marzán

Poster presentation | Universal self-assembly process of differently shaped nanoparticles

International Workshop on Self-assembly and Hierarchical Materials in Biomedicine - Poster presentation

M. Charconnet, C. Hanske, C. Matricardi, A. Mihi, A. Seifert, L. Liz-Marza?n

2017

Invited talk | Photonic methods & devices in medical diagnostics

6th Global (NANJING) R&D Summit - Invited talk

Andreas Seifert

Invited talk | Novel innovations in photonic medical diagnostics

The International Industrial and Technological Innovation Summit (Xuzhou) on Bio-Material and Medical Equipment and the Special Activities of International Innovation Conference on EU Project Roadshow - Invited talk

Andreas Seifert

2016

Poster presentation | Self-assembled monolayers on graphene

International Conference on Self-Assembly in Confined Spaces - Poster presentation

MC Morant-Miñana, E Lopez, A Seifert

Poster presentation | Cardiovascular monitoring based on arterial distension

EMBS Micro and Nanotechnology in Medicine Conference - Poster presentation

D Ruh, A Seifert